[HTML][HTML] Malaria vaccines: progress to date

DI Stanisic, MF Good - BioDrugs, 2023 - Springer
Malaria is a mosquito-borne disease caused by protozoan parasites of the genus
Plasmodium. Despite significant declines in malaria-attributable morbidity and mortality over …

RTS, S/AS01 vaccine (Mosquirix™): an overview

MB Laurens - Human vaccines & immunotherapeutics, 2020 - Taylor & Francis
Malaria is an illness caused by Plasmodium parasites transmitted to humans by infected
mosquitoes. Of the five species that infect humans, P. falciparum exacts the highest toll in …

Malaria vaccine: prospects and challenges

AO Hassan, OV Oso, EI Obeagu… - … University journal of …, 2022 - madonnauniversity.edu.ng
Malaria is a life-threatening disease caused by the plasmodium genus, malaria can cause a
range of symptoms and life–threatening complications so an early diagnosis is crucial. In …

[HTML][HTML] Malaria vaccines: the 60-year journey of hope and final success—lessons learned and future prospects

AA El-Moamly, MA El-Sweify - Tropical Medicine and Health, 2023 - Springer
Background The world has made great strides towards beating malaria, although about half
of the world population is still exposed to the risk of contracting malaria. Developing an …

The RTS, S malaria vaccine

S Casares, TD Brumeanu, TL Richie - Vaccine, 2010 - Elsevier
RTS, S is the most advanced candidate vaccine against human malaria. During its
remarkable journey from conception and design in the early 1980s to the multicenter Phase …

[HTML][HTML] Advances and challenges in malaria vaccine development

PD Crompton, SK Pierce… - The Journal of clinical …, 2010 - Am Soc Clin Investig
Malaria caused by Plasmodium falciparum remains a major public health threat, especially
among children and pregnant women in Africa. An effective malaria vaccine would be a …

[HTML][HTML] RTS,S/AS01 malaria vaccine (Mosquirix®): a profile of its use

YY Syed - Drugs & Therapy Perspectives, 2022 - Springer
Abstract RTS, S/AS01 (Mosquirix®) is a vaccine against malaria caused by Plasmodium
falciparum. In a phase 3 trial, RTS, S/AS01 showed vaccine efficacy against clinical malaria …

[HTML][HTML] Mosquirix™ RTS, S/AS01 vaccine development, immunogenicity, and efficacy

AY Nadeem, A Shehzad, SU Islam, EA Al-Suhaimi… - Vaccines, 2022 - mdpi.com
Malaria is a parasitic infection caused by bites from Plasmodium falciparum (P. falciparum)-
infected mosquitoes with a present scale of symptoms ranging from moderate fever to …

The march toward malaria vaccines

SL Hoffman, J Vekemans, TL Richie, PE Duffy - Vaccine, 2015 - Elsevier
In 2013 there were an estimated 584,000 deaths and 198 million clinical illnesses due to
malaria, the majority in sub-Saharan Africa. Vaccines would be the ideal addition to the …

Malaria vaccine R&D in the Decade of Vaccines: breakthroughs, challenges and opportunities

AJ Birkett, VS Moorthy, C Loucq, CE Chitnis… - Vaccine, 2013 - Elsevier
While recent progress has been made in reducing malaria mortality with other interventions,
vaccines are still urgently needed to further reduce the incidence of clinical disease …