Anticholinergic medication burden–associated cognitive impairment in schizophrenia

YB Joshi, ML Thomas, DL Braff… - American Journal of …, 2021 - Am Psychiatric Assoc
Objective: Many psychotropic medications used to treat schizophrenia have significant
anticholinergic properties, which are linked to cognitive impairment and dementia risk in …

Cognitive burden of anticholinergic medications in psychotic disorders

S Eum, SK Hill, LH Rubin, RM Carnahan, JL Reilly… - Schizophrenia …, 2017 - Elsevier
Background Patients with psychotic disorders are often treated with numerous medications,
many of which have anticholinergic activity. We assessed cognition in relation to the …

The cognitive cost of anticholinergic burden: decreased response to cognitive training in schizophrenia

S Vinogradov, M Fisher, H Warm… - American Journal of …, 2009 - Am Psychiatric Assoc
Objective: Schizophrenia is treated with medications that raise serum anticholinergic activity
and are known to adversely affect cognition. The authors examined the relationship between …

Antipsychotic medication and cognitive function in schizophrenia

H Hori, H Noguchi, R Hashimoto, T Nakabayashi… - Schizophrenia …, 2006 - Elsevier
Antipsychotic polypharmacy and excessive dosing still prevail worldwide in the treatment of
schizophrenia, while their possible association with cognitive function has not well been …

Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial

RSE Keefe, RM Bilder, SM Davis… - Archives of general …, 2007 - jamanetwork.com
Context Neurocognitive impairment in schizophrenia is severe and is an important predictor
of functional outcome. The relative effect of the second-generation (atypical) antipsychotic …

Profiling cognitive impairment in treatment-resistant schizophrenia patients

D Frydecka, JA Beszłej, P Gościmski, A Kiejna… - Psychiatry …, 2016 - Elsevier
The aim of this study was to compare cognitive performance between schizophrenia patients
with and without treatment resistance (TRS and non-TRS patients) taking into account …

Neurocognitive impairment in schizophrenia and how it affects treatment options

RM Bilder - The Canadian Journal of Psychiatry, 1997 - journals.sagepub.com
Objective To review the roles played by neurocognitive assessment in the treatment of
schizophrenia and in the design of treatment research strategies. Method A review of the …

Cognitive effects of antipsychotic dosage and polypharmacy: a study with the BACS in patients with schizophrenia and schizoaffective disorder

D Elie, M Poirier, JM Chianetta… - Journal of …, 2010 - journals.sagepub.com
Antipsychotic polypharmacy and high doses have been associated with poorer outcome,
longer hospital stays, and increased side effects. The present naturalistic study assessed the …

Association of anticholinergic load with impairment of complex attention and memory in schizophrenia

MJ Minzenberg, JH Poole, C Benton… - American Journal of …, 2004 - Am Psychiatric Assoc
OBJECTIVE: The authors' goals were 1) to establish a clinically useful standard index of the
relative anticholinergic potency of psychiatric medications; 2) to determine which cognitive …

A brief cognitive assessment for use with schizophrenia patients in community clinics

DI Velligan, M DiCocco, CC Bow-Thomas, C Cadle… - Schizophrenia …, 2004 - Elsevier
Cognitive impairment is a prominent feature of schizophrenia. The availability of very brief
measures may increase the use of cognitive assessment in routine care settings. We …