Background Although constipation can be a chronic and severe problem, it is largely treated
empirically. Evidence for the efficacy of some of the older laxatives from well‐designed trials …

BACKGROUND: Constipation is an uncomfortable and common condition that affects many,
irrespective of age. Since 1500 BC and before, health care practitioners have provided …

Chronic constipation is a common condition that affects up to 27% of the population. Dietary
and lifestyle measures are usually the first-line therapy, but if these fail to have an effect then …

Pharmacological management of constipation Page 1 Pharmacological management of
constipation AV EMMANUEL,* J. TACK, EM QUIGLEYà & NJ TALLEY§ *Physiology Unit …

Background Chronic constipation is a common, heterogeneous disorder with multiple
symptoms and pathophysiological mechanisms. Patients are often referred to a …

Background There has been no definitive systematic review and meta-analysis to date
examining the effect of laxatives and pharmacological therapies in chronic idiopathic …

Chronic constipation (CC) is an extremely common condition with an estimated prevalence
of up to 24%. Most patients with CC should be treated in primary care. Changes in lifestyle …

Chronic constipation is a common, persistent condition affecting many patients worldwide,
presenting significant economic burden and resulting in substantial healthcare utilization. In …

ABSTRACT BACKGROUND Chronic constipation is a prevalent disorder that affects
patients' quality of life and consumes resources in healthcare systems worldwide. In clinical …

Only a relatively small percentage of clinically constipated patients seek medical attention
and most can be managed satisfactorily with conservative measures. This review mainly …