Tracer-kinetic modeling of dynamic contrast-enhanced MRI and CT: a primer

M Ingrisch, S Sourbron - Journal of pharmacokinetics and …, 2013 - Springer
Dynamic contrast-enhanced computed tomography (DCE-CT) and magnetic resonance
imaging (DCE-MRI) are functional imaging techniques. They aim to characterise the …

Determination of pharmacokinetic parameters in DCE MRI: consequence of nonlinearity between contrast agent concentration and signal intensity

M Heilmann, F Kiessling, M Enderlin… - Investigative …, 2006 - journals.lww.com
Objectives: We sought to compare pharmacokinetic modeling of dynamic contrast-enhanced
magnetic resonance imaging (DCE-MRI) data by assuming a linear and nonlinear …

Evolution from empirical dynamic contrast-enhanced magnetic resonance imaging to pharmacokinetic MRI

JS Taylor, WE Reddick - Advanced drug delivery reviews, 2000 - Elsevier
For chemotherapy to be effective against cancers which grow as solid tumors, agents must
reach all tumor cells in effective quantities. Although many clinical trials include studies of …

Accuracy and precision of quantitative DCE-MRI parameters: How should one estimate contrast concentration?

N Wake, H Chandarana, H Rusinek, K Fujimoto… - Magnetic resonance …, 2018 - Elsevier
Introduction Pharmacokinetic parameters derived from dynamic contrast-enhanced MRI
(DCE-MRI) data are sensitive to acquisition and post-processing techniques, which makes it …

DCE@ urLAB: a dynamic contrast-enhanced MRI pharmacokinetic analysis tool for preclinical data

JE Ortuño, MJ Ledesma-Carbayo, RV Simões… - BMC …, 2013 - Springer
Background DCE@ urLAB is a software application for analysis of dynamic contrast-
enhanced magnetic resonance imaging data (DCE-MRI). The tool incorporates a friendly …

Relative sensitivities of DCE-MRI pharmacokinetic parameters to arterial input function (AIF) scaling

X Li, Y Cai, B Moloney, Y Chen, W Huang… - Journal of Magnetic …, 2016 - Elsevier
Abstract Dynamic-Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) has been
used widely for clinical applications. Pharmacokinetic modeling of DCE-MRI data that …

Dynamic contrast enhanced magnetic resonance imaging in oncology: theory, data acquisition, analysis, and examples

TE Yankeelov, JC Gore - Current Medical Imaging, 2007 - ingentaconnect.com
Dynamic contrast enhanced MRI (DCE-MRI) enables the quantitative assessment of tumor
status and has found application in both pre-clinical tumor models as well as clinical …

Tracer kinetic modelling of tumour angiogenesis based on dynamic contrast-enhanced CT and MRI measurements

G Brix, J Griebel, F Kiessling, F Wenz - European journal of nuclear …, 2010 - Springer
Purpose Technical developments in both magnetic resonance imaging (MRI) and computed
tomography (CT) have helped to reduce scan times and expedited the development of …

Signal-to-noise ratio, contrast-to-noise ratio and pharmacokinetic modeling considerations in dynamic contrast-enhanced magnetic resonance imaging

X Li, W Huang, WD Rooney - Magnetic resonance imaging, 2012 - Elsevier
With advances in magnetic resonance imaging (MRI) technology, dynamic contrast-
enhanced (DCE)-MRI is approaching the capability to simultaneously deliver both high …

Dynamic magnetic resonance imaging of tumor perfusion

DJ Collins, AR Padhani - IEEE Engineering in Medicine and …, 2004 - ieeexplore.ieee.org
This work presents approaches and biomedical challenges of dynamic contrast enhanced
magnetic resonance imaging (DCE-MRI). DCE-MRI using small molecular weight …