A review of the interactions between alcohol and the endocannabinoid system: implications for alcohol dependence and future directions for research

MJ Pava, JJ Woodward - Alcohol, 2012 - Elsevier
Over the past fifty years a significant body of evidence has been compiled suggesting an
interaction between the endocannabinoid (EC) system and alcohol dependence. However …

Endocannabinoid system and alcohol abuse disorders

BS Basavarajappa - Recent Advances in Cannabinoid Physiology and …, 2019 - Springer
Abstract Δ 9-tetrahydrocannabinol (Δ 9-THC), the primary active component in Cannabis
sativa preparations such as hashish and marijuana, signals by binding to cell surface …

Neuromodulatory role of the endocannabinoid signaling system in alcoholism: an overview

BS Basavarajappa, BL Hungund - Prostaglandins, Leukotrienes and …, 2002 - Elsevier
The current review evaluates the evidence that some of the pharmacological and behavioral
effects of ethanol (EtOH), including EtOH-preferring behavior, may be mediated through the …

Roles for the endocannabinoid system in ethanol-motivated behavior

AN Henderson-Redmond, J Guindon… - Progress in Neuro …, 2016 - Elsevier
Alcohol use disorder represents a significant human health problem that leads to substantial
loss of human life and financial cost to society. Currently available treatment options do not …

Interactions between cannabinoid and opioid receptor systems in the mediation of ethanol effects

J Manzanares, S Ortiz, JM Oliva… - Alcohol and …, 2005 - academic.oup.com
Over the past few years, advances in the investigation of the neurochemical circuits involved
in the development and treatment of alcohol dependence have identified peptides and …

Role of endocannabinoids and cannabinoid CB1 receptors in alcohol‐related behaviors

BL Hungund, BS Basavarajappa - … of the New York Academy of …, 2004 - Wiley Online Library
This review presents the remarkable research during the past several years indicating that
some of the pharmacological and behavioral effects of alcohol, including alcohol drinking …

Decreased alcohol self-administration and increased alcohol sensitivity and withdrawal in CB1 receptor knockout mice

M Naassila, O Pierrefiche, C Ledent, M Daoust - Neuropharmacology, 2004 - Elsevier
Recent advances in the understanding of the neurobiological basis of alcohol dependence
suggest that the endocannabinoid system may play a key role in the reinforcing effects of …

Distinct functions of endogenous cannabinoid system in alcohol abuse disorders

BS Basavarajappa, V Joshi… - British Journal of …, 2019 - Wiley Online Library
Δ9‐tetrahydrocannabinol, the principal active component in Cannabis sativa extracts such
as marijuana, participates in cell signalling by binding to cannabinoid CB1 and CB2 …

Interactions between alcohol and the endocannabinoid system

G Kunos - Alcoholism: Clinical and Experimental Research, 2020 - Wiley Online Library
Endocannabinoids are lipid mediators that interact with the same cannabinoid receptors that
recognize Δ9‐tetrahydrocannabinol (THC), the psychoactive constituent of marijuana, to …

The endocannabinoid signaling system: a potential target for next-generation therapeutics for alcoholism

BS Basavarajappa - Mini reviews in medicinal chemistry, 2007 - ingentaconnect.com
Research into the endocannabinoid signaling system has grown exponentially in recent
years following the discovery of cannabinoid receptors (CB) and their endogenous ligands …