[HTML][HTML] Anti-LL37 antibodies are present in psoriatic arthritis (PsA) patients: new biomarkers in PsA
Psoriatic arthritis (PsA) is a chronic inflammatory arthritis associated with psoriasis. A third of
psoriatic patients develop PsA via unknown mechanisms. No reliable diagnostic markers …
psoriatic patients develop PsA via unknown mechanisms. No reliable diagnostic markers …
[HTML][HTML] Native/citrullinated LL37-specific T-cells help autoantibody production in Systemic Lupus Erythematosus
R Lande, R Palazzo, N Gestermann, C Jandus… - Scientific reports, 2020 - nature.com
LL37 exerts a dual pathogenic role in psoriasis. Bound to self-DNA/RNA, LL37 licenses
autoreactivity by stimulating plasmacytoid dendritic cells-(pDCs)-Type I interferon (IFN-I) and …
autoreactivity by stimulating plasmacytoid dendritic cells-(pDCs)-Type I interferon (IFN-I) and …
Identification of novel autoantibodies associated with psoriatic arthritis
Objective The autoimmune etiology in psoriasis remains to be clarified. We therefore
undertook this study to identify novel pathogenic autoantigens and autoantibodies in …
undertook this study to identify novel pathogenic autoantigens and autoantibodies in …
[HTML][HTML] The antimicrobial peptide LL37 is a T-cell autoantigen in psoriasis
R Lande, E Botti, C Jandus, D Dojcinovic… - Nature …, 2014 - nature.com
Psoriasis is a common T-cell-mediated skin disease with 2–3% prevalence worldwide.
Psoriasis is considered to be an autoimmune disease, but the precise nature of the …
Psoriasis is considered to be an autoimmune disease, but the precise nature of the …
[HTML][HTML] Cathelicidin LL-37: A new important molecule in the pathophysiology of systemic lupus erythematosus
A Moreno-Angarita, CC Aragón, GJ Tobón - Journal of translational …, 2020 - Elsevier
Cathelicidin LL-37 is an antimicrobial peptide that is synthesized by epithelial cells,
neutrophils, or lymphocytes and act as an essential defense mechanism against bacterial …
neutrophils, or lymphocytes and act as an essential defense mechanism against bacterial …
Autoantigens ADAMTSL 5 and LL 37 are significantly upregulated in active Psoriasis and localized with keratinocytes, dendritic cells and other leukocytes
J Fuentes‐Duculan, KM Bonifacio… - Experimental …, 2017 - Wiley Online Library
Psoriasis is a common immune‐mediated disease that affects 2%‐4% of individuals in North
America and Europe. In the past decade, advances in research have led to an improved …
America and Europe. In the past decade, advances in research have led to an improved …
Current knowledge on autoantigens and autoantibodies in psoriasis
LL Ten Bergen, A Petrovic… - … Journal of Immunology, 2020 - Wiley Online Library
In the past decades, clinical and experimental evidence has demonstrated that psoriasis is
an immune‐mediated inflammatory disease of the skin that occurs in genetically susceptible …
an immune‐mediated inflammatory disease of the skin that occurs in genetically susceptible …
The contribution of IL-17 to the development of autoimmunity in psoriasis
Psoriasis is an (auto) immune-mediated disease that manifests as widespread
desquamative erythema. The TNF-α/IL-23/IL-17A axis is crucial to its pathogenesis, which is …
desquamative erythema. The TNF-α/IL-23/IL-17A axis is crucial to its pathogenesis, which is …
Arthritis in systemic lupus erythematosus is characterized by local IL-17A and IL-6 expression in synovial fluid
N Sippl, F Faustini, J Rönnelid… - Clinical & …, 2021 - academic.oup.com
Arthritis is a common clinical feature of systemic lupus erythematosus (SLE) and is usually
non-erosive, as opposed to rheumatoid arthritis (RA). While RA synovial pathology has been …
non-erosive, as opposed to rheumatoid arthritis (RA). While RA synovial pathology has been …
The Th17/IL‐23 axis and natural immunity in psoriatic arthritis
S Maeda, Y Hayami, T Naniwa… - International journal of …, 2012 - Wiley Online Library
Psoriatic arthritis (PsA) is a chronic inflammatory skin disease that causes enthesitis and
destructive arthritis and significantly lowers patient quality of life. Recognition of the two …
destructive arthritis and significantly lowers patient quality of life. Recognition of the two …