Eugenol induces apoptosis in tongue squamous carcinoma cells by mediating the expression of Bcl-2 family

DA Surducan, RC Racea, M Cabuta, I Olariu, I Macasoi… - Life, 2022 - mdpi.com
Head and neck squamous cell carcinoma is highly aggressive type of cancer for which the
available treatment often causes patients severe side effects. Eugenol (Eug) is the major …

[PDF][PDF] S phase cell cycle arrest and apoptosis is induced by eugenol in G361 human melanoma cells

BB Rachoi, SH Shin, UK Kim, JW Hong… - International Journal of …, 2011 - koreascience.kr
Eugenol is an essential oil found in cloves and cinnamon that is used widely in perfumes.
However, the significant anesthetic and sedative effects of this compound have led to its use …

The effect of eugenol on the induction of apoptosis in HSC-2 human oral squamous cell carcinoma

YH Kim, BS Park - Journal of Korean society of Dental Hygiene, 2015 - koreascience.kr
Objectives: Oropharynx tumors (oral cancer), are caused by tobacco, alcohol consumption,
and high-risk human papillomavirus (HPV) infection. Oral squamous cell carcinoma (OSCC) …

Eugenol exerts apoptotic effect and modulates the sensitivity of HeLa cells to cisplatin and radiation

M Fathy, MA Fawzy, H Hintzsche, T Nikaido… - Molecules, 2019 - mdpi.com
Eugenol is a phytochemical present in different plant products, eg, clove oil. Traditionally, it
is used against a number of different disorders and it was suggested to have anticancer …

A comprehensive and systematic review on potential anticancer activities of eugenol: From pre-clinical evidence to molecular mechanisms of action

SN Begum, AS Ray, CH Rahaman - Phytomedicine, 2022 - Elsevier
Abstract Background Eugenol (1-allyl-4-hydroxy-3-methoxybenzene) is an important simple
phenolic compound mainly derived from Syzygium aromaticum and many other plants. It is …

Apoptotic effect of eugenol in human colon cancer cell lines

SK Jaganathan, A Mazumdar, D Mondhe… - Cell biology …, 2011 - Wiley Online Library
Eugenol, a natural compound available in honey and various plants extracts including
cloves and Magnoliae flos, is exploited for various medicinal applications. Since most of the …

Aloe-emodin induces apoptosis in human oral squamous cell carcinoma SCC15 cells

Q Li, J Wen, K Yu, Y Shu, W He, H Chu… - … and alternative medicine, 2018 - Springer
Background Oral and pharyngeal cancer is the most common malignant human cancers.
Chemotherapy is an effective approach for anti-oral cancer therapy, while the drug tolerance …

[PDF][PDF] Eugenol: in vitro characterization of the cytotoxic profile at the level of colorectal carcinoma cells

RC Racea, PE Merghes, D Gurgus, I Macasoi… - …, 2023 - farmaciajournal.com
In the present study, the main objective was to evaluate the cytotoxic potential of eugenol on
colorectal carcinoma cells-HCT-116, as well as on healthy human keratinocytes-HaCaT …

Antiproliferative and molecular mechanism of eugenol-induced apoptosis in cancer cells

SK Jaganathan, E Supriyanto - Molecules, 2012 - mdpi.com
Phenolic phytochemicals are a broad class of nutraceuticals found in plants which have
been extensively researched by scientists for their health-promoting potential. One such a …

Eugenol: In Vitro and In Ovo Assessment to Explore Cytotoxic Effects on Osteosarcoma and Oropharyngeal Cancer Cells

RC Racea, IG Macasoi, S Dinu, I Pinzaru, I Marcovici… - Plants, 2023 - mdpi.com
Cancer is a significant health problem worldwide; consequently, new therapeutic
alternatives are being investigated, including those found in the vegetable kingdom …