Background Radiotherapy can cause kidney injury in patients with cervical cancer. This
study aims to investigate the possible molecular mechanisms by which CpG-ODNs …

Upregulation of NADPH oxidases (NOXs) in cancer cells leads to chronic increase in
intracellular reactive oxygen species (ROS) and adaptation to a high ROS level for cell …

Background the bone marrow and the intestine are the major sites of ionizing radiation (IR)-
induced injury. Our previous study demonstrated that CpG-oligodeoxynucleotide (ODN) …

Purpose Cervical cancer (CC) is the fourth most common cancer with high death rate in
females. The study aims to detect the mechanism of long non-coding RNA (LncRNA) PCAT1 …

Radiotherapy (RT) is an effective curative cancer treatment. However, RT can seriously
damage kidney tissues resulting in radiotherapy nephropathy (RN) where oxidative stress …

Objective To evaluate the anti-cancer effect of unmethylated cytosine-phosphorothioate-
guanine (CpG)-containing oligodeoxynucleotides (ODNs) on human bladder cancer UM-UC …

Purpose: Radiotherapy (RT) is one of the major treatments of cervical cancer. Although the
prognosis of clinical cervical cancer becomes better in recent years, some patients still suffer …

Cervical cancer as a common gynecological malignancy threatens the health and lives of
women. Resistance to radiotherapy is the primary cause of treatment failure and is mainly …

Acute renal failure is a serious complication of treatment with the anticancer drug cisplatin.
Cisplatin exerts a cytotoxic effect on renal cells by inducing apoptosis through activating the …

The present study was to investigate the effects of DNA-PKcs deficiencies on radiation
sensitivity of human osteosarcoma U2OS cells to γ-ray and to explore the underlying …