The escalating social and economic burden of an aging world population has placed aging
research at center stage. The hallmarks of aging comprise diverse molecular mechanisms …

Telomeres are the protective end-complexes at the termini of eukaryotic chromosomes.
Telomere attrition can lead to potentially maladaptive cellular changes, block cell division …

Ageing organisms accumulate senescent cells that are thought to contribute to body
dysfunction. Telomere shortening and damage are recognized causes of cellular …

Telomeres are dynamic chromosome-end structures that serve as guardians of genome
stability. They are known to be one of the major determinants of aging and longevity in …

Telomeres are the repetitive DNA sequences and specialized proteins that form the
distinctive structure that caps the ends of linear chromosomes. Telomeres allow cells to …

Telomeres are protective structures present at the ends of linear chromosomes that are
important in preventing genome instability. Telomeres shorten as a result of cellular …

Telomeres are the specialized DNA–protein structures that cap the ends of linear
chromosomes, thereby protecting them from degradation and fusion by cellular DNA repair …

Telomeres in telomerase-negative cells shorten during DNA replication in vitro due to
numerous causes including the inability of DNA polymerases to fully copy the lagging …

Can telomere dynamics, defined by telomere length and attrition rate, provide information
about the biology of human aging above and beyond that provided by chronological age …

Telomeres, the protective ends of linear chromosomes, shorten throughout an individual's
lifetime. Telomere shortening is a hallmark of molecular aging and is associated with …