RNA molecules have recently become attractive as potential drug targets due to the
increased awareness of their importance in key biological processes. The increase of the …

The ability to accurately predict the binding site, binding pose, and binding affinity for ligand–
RNA binding is important for RNA-targeted drug design. Here, we describe a new …

RNA molecules play critical roles in cellular functions at the level of gene expression and
regulation. The intricate 3D structures and the functional roles of RNAs make RNA …

With rapid advances in computer algorithms and hardware, fast and accurate virtual
screening has led to a drastic acceleration in selecting potent small molecules as drug …

With an increasing interest in RNA therapeutics and for targeting RNA to treat disease, there
is a need for the tools used in protein-based drug design, particularly DOCKing algorithms …

RNA-small molecule binding is a key regulatory mechanism which can stabilize 3D
structures and activate molecular functions. The discovery of RNA-targeting compounds is …

Substantial progress in RNA biology highlights the importance of RNAs (eg, microRNAs) in
diseases and the potential of targeting RNAs for drug discovery. However, the lack of RNA …

There is growing interest in RNA as a drug target due to its widespread involvement in
biological processes. To exploit the power of structure-based drug-design approaches …

RNA is considered as an attractive target for new small molecule drugs. Designing active
compounds can be facilitated by computational modeling. Most of the available tools …

Ribonucleic acids (RNAs), particularly the noncoding RNAs, play key roles in cancer,
making them attractive drug targets. While conventional methods such as high throughput …