A Peptide-Based Oscillator

D Dev, N Wagner, B Pramanik, B Sharma… - Journal of the …, 2023 - ACS Publications
Living organisms are replete with rhythmic and oscillatory behavior at all levels, to the extent
that oscillations have been termed as a defining attribute of life. Recent studies of synthetic …

Coupled oscillations and circadian rhythms in molecular replication networks

N Wagner, S Alasibi, E Peacock-Lopez… - The journal of …, 2015 - ACS Publications
Living organisms often display rhythmic and oscillatory behavior. We investigate here a
challenge in contemporary Systems Chemistry, that is, to construct “bottom-up” molecular …

Entrainment of a bacterial synthetic gene oscillator through proteolytic queueing

NC Butzin, P Hochendoner, CT Ogle… - ACS synthetic …, 2017 - ACS Publications
Internal chemical oscillators (chemical clocks) direct the behavior of numerous biological
systems, and maintenance of a given period and phase among many such oscillators may …

A catalytically active oscillator made from small organic molecules

M Ter Harmsel, OR Maguire, SA Runikhina, ASY Wong… - Nature, 2023 - nature.com
Oscillatory systems regulate many biological processes, including key cellular functions
such as metabolism and cell division, as well as larger-scale processes such as circadian …

Systems and synthetic biology approaches in understanding biological oscillators

Z Li, Q Yang - Quantitative Biology, 2018 - Wiley Online Library
Background Self‐sustained oscillations are a ubiquitous and vital phenomenon in living
systems. From primitive single‐cellular bacteria to the most sophisticated organisms …

Role of fast and slow inhibitors in oscillatory rhythm design

H Wang, Z Cheng, L Yuan, L Ren, C Pan… - Journal of the …, 2023 - ACS Publications
In biological or abiotic systems, rhythms occur, owing to the coupling between positive and
negative feedback loops in a reaction network. Using the Semenov–Whitesides oscillatory …

A synthetic population-level oscillator in non-microfluidic environments

F Gu, W Jiang, F Kang, T Su, X Yang, Q Qi… - Communications …, 2023 - nature.com
Synthetic oscillators have become a research hotspot because of their complexity and
importance. The construction and stable operation of oscillators in large-scale environments …

A chemically fueled non-enzymatic bistable network

I Maity, N Wagner, R Mukherjee, D Dev… - Nature …, 2019 - nature.com
One of the grand challenges in contemporary systems chemistry research is to mimic life-like
functions using simple synthetic molecular networks. This is particularly true for systems that …

Design principles for robust oscillatory behavior

SM Castillo-Hair, ER Villota, AM Coronado - Systems and synthetic biology, 2015 - Springer
Oscillatory responses are ubiquitous in regulatory networks of living organisms, a fact that
has led to extensive efforts to study and replicate the circuits involved. However, to date …

Chemomechanical oscillations with a non-redox non-oscillatory reaction

J Horváth - Chemical Communications, 2017 - pubs.rsc.org
Periodic length changes, over 20%, were sustained in a pH-responsive gel by associating
the methylene glycol–sulphite OH-producing clock-reaction with variations of the exchange …