[HTML][HTML] The emerging role of fatty acid binding protein 5 (FABP5) in cancers
WG Warren, M Osborn, A Yates, K Wright… - Drug Discovery …, 2023 - Elsevier
Highlights•Fatty acid binding protein 5 (FABP5) is a key regulator of cell metabolism and
growth that is overexpressed in cancers.•FABP5 facilitates the activation of transcriptional …
growth that is overexpressed in cancers.•FABP5 facilitates the activation of transcriptional …
Therapeutic implications of FABP4 in cancer: an emerging target to tackle cancer
N Sun, X Zhao - Frontiers in Pharmacology, 2022 - frontiersin.org
Metabolic reprogramming is an emerging hallmark of tumor cells. In order to survive in
nutrient-deprived environment, tumor cells rewire their metabolic phenotype to provide …
nutrient-deprived environment, tumor cells rewire their metabolic phenotype to provide …
The fatty acid binding protein 7 (FABP7) is involved in proliferation and invasion of melanoma cells
A Slipicevic, K Jørgensen, M Skrede, AKR Rosnes… - BMC cancer, 2008 - Springer
Background The molecular mechanisms underlying melanoma tumor development and
progression are still not completely understood. One of the new candidates that emerged …
progression are still not completely understood. One of the new candidates that emerged …
[HTML][HTML] Fatty acid binding protein 5 promotes metastatic potential of triple negative breast cancer cells through enhancing epidermal growth factor receptor stability
Fatty acid binding protein 5 (FABP5), an intracellular lipid binding protein, has been shown
to play a role in various cancers, including breast cancer. However, FABP5 and its role in …
to play a role in various cancers, including breast cancer. However, FABP5 and its role in …
Role of FABP7 in tumor cell signaling
Lipids are major molecules for the function of organisms and are involved in the
pathophysiology of various diseases. Fatty acids (FAs) signaling and their metabolism are …
pathophysiology of various diseases. Fatty acids (FAs) signaling and their metabolism are …
High expression of fatty acid‐binding protein 5 promotes cell growth and metastatic potential of colorectal cancer cells
K Kawaguchi, S Senga, C Kubota, Y Kawamura… - FEBS open …, 2016 - Wiley Online Library
Fatty acid‐binding proteins (FABP s) are responsible for binding and storing hydrophobic
ligands such as long‐chain fatty acids, and for transporting these ligands to the appropriate …
ligands such as long‐chain fatty acids, and for transporting these ligands to the appropriate …
Altered fatty acid‐binding protein 4 (FABP 4) expression and function in human and animal models of hepatocellular carcinoma
KJ Thompson, RG Austin, SS Nazari… - Liver …, 2018 - Wiley Online Library
Abstract Background and Aims Hepatocellular carcinoma (HCC) is the third leading cause of
cancer‐related mortality. Risk factors for developing HCC include viral hepatitis, alcohol and …
cancer‐related mortality. Risk factors for developing HCC include viral hepatitis, alcohol and …
Fatty acid-binding protein 5 (FABP5) promotes lipolysis of lipid droplets, de novo fatty acid (FA) synthesis and activation of nuclear factor-kappa B (NF-κB) signaling in …
S Senga, N Kobayashi, K Kawaguchi, A Ando… - Biochimica et Biophysica …, 2018 - Elsevier
Fatty acid-binding proteins (FABPs) are involved in binding and storing hydrophobic ligands
such as long-chain fatty acids, as well as transporting them to the appropriate compartments …
such as long-chain fatty acids, as well as transporting them to the appropriate compartments …
FABP5 is correlated with poor prognosis and promotes tumour cell growth and metastasis in clear cell renal cell carcinoma
G Wu, Y Xu, Q Wang, J Li, L Li, C Han, Q Xia - European Journal of …, 2019 - Elsevier
To support proliferation, tumour cells often undergo a metabolic switch to aerobic glycolysis,
and a large amount of fatty acids (FAs) is produced to provide conditions for the formation of …
and a large amount of fatty acids (FAs) is produced to provide conditions for the formation of …
Expression of fatty acid binding protein 4 is involved in the cell growth of oral squamous cell carcinoma
D Lee, K Wada, Y Taniguchi… - Oncology …, 2014 - spandidos-publications.com
Fatty acid binding proteins (FABPs) are a family of small and highly conserved lipid
chaperone molecules with highly varied functions. Among them, fatty acid binding protein 4 …
chaperone molecules with highly varied functions. Among them, fatty acid binding protein 4 …
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