The panoramic view of amyotrophic lateral sclerosis: A fatal intricate neurological disorder

S Dhasmana, A Dhasmana, AS Narula, M Jaggi… - Life Sciences, 2022 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurological disease affecting
both upper and lower motor neurons. In the United States alone, there are 16,000–20,000 …

Amyotrophic lateral sclerosis from bench to bedside

C Lomen-Hoerth - Seminars in neurology, 2008 - thieme-connect.com
Amyotrophic lateral sclerosis (ALS) is a progressive disease for which there are currently no
significant treatments to alter the fatal outcome. The cause of the disease is still elusive …

[HTML][HTML] Clinical manifestation and management of amyotrophic lateral sclerosis

A Verma - 2021 - europepmc.org
Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive neurodegenerative disease
resulting in death in 2 to 4 years in most cases. There are several clinical subtypes of ALS …

Clinical spectrum of amyotrophic lateral sclerosis (ALS)

LI Grad, GA Rouleau, J Ravits… - Cold Spring …, 2017 - perspectivesinmedicine.cshlp.org
Amyotrophic lateral sclerosis (ALS) is primarily characterized by progressive loss of motor
neurons, although there is marked phenotypic heterogeneity between cases. Typical, or …

Amyotrophic lateral sclerosis–looking for pathogenesis and effective therapy

E Naganska, E Matyja - Folia Neuropathologica, 2011 - termedia.pl
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease
characterized by loss of motor neurons in the spinal cord, brain stem and motor cortex which …

Understanding the causes of amyotrophic lateral sclerosis

RW Orrell - New England Journal of Medicine, 2007 - Mass Medical Soc
Amyotrophic lateral sclerosis (ALS) is a human disease resulting from the degeneration of
motor neurons in the brain, spinal cord, and peripheral nervous system. The resultant …

Diagnosis and clinical management of amyotrophic lateral sclerosis and other motor neuron disorders

SA Goutman - CONTINUUM: Lifelong Learning in Neurology, 2017 - journals.lww.com
Abstract Purpose of Review: This article reviews the clinical features, diagnostic pathway,
therapies, and current understanding of the pathophysiology of amyotrophic lateral sclerosis …

Amyotrophic lateral sclerosis

CE Jackson, WW Bryan - Seminars in neurology, 1998 - thieme-connect.com
Amyotrophic lateral sclerosis (ALS) is a motor neuron disease with evidence of both anterior
horn cell and corticospinal tract degeneration. The incidence of ALS is 1 to 2.5 cases per …

Amyotrophic lateral sclerosis: update on clinical management

SP Norris, MFN Likanje… - Current opinion in …, 2020 - journals.lww.com
ALS is a progressive neurodegenerative disease that causes degeneration of the motor
neurons which leads to paralysis and respiratory failure. Despite the lack of a cure …

[HTML][HTML] A comprehensive review of amyotrophic lateral sclerosis

S Zarei, K Carr, L Reiley, K Diaz, O Guerra… - Surgical neurology …, 2015 - ncbi.nlm.nih.gov
Amyotrophic lateral sclerosis (ALS) is a late-onset fatal neurodegenerative disease affecting
motor neurons with an incidence of about 1/100,000. Most ALS cases are sporadic, but 5 …