Most cases of serotonin toxicity are provoked by therapeutic doses of a combination of two
or more serotonergic drugs, defined as drugs affecting the serotonin neurotransmitter …

Toxicity resulting from excessive intra-synaptic serotonin, historically referred to as serotonin
syndrome, is now understood to be an intra-synaptic serotonin concentration-related …

Serotonin (5-hydroxytryptamine) is an important biogenic amine that fulfills the role of
neurotransmitter and neuromodulator. It has been a focus of interest during the last decade …

Serotonin syndrome results from excessive activation of serotonin (5-hydroxytryptamine; 5-
HT) receptors in the nervous system, on the surface of platelets, and on the vascular …

A reply We agree that it would have been interesting to know how many units are routinely
using hand-held ultrasound of the neck as a prelude to percutaneous tracheostomy. We …

Purpose To report a case of serotonin toxicity, presenting in the postoperative period,
caused by an interaction between paroxetine (a selective serotonin reuptake inhibitor, SSRI) …

The newer, selective serotonin reuptake inhibitors are increasingly used in psychiatry in
both children and adults. Although they have fewer side‐effects, they can cause significant …

Serotonin toxicity (or serotonin syndrome) has become an increasingly common and
important clinical problem in medicine over the last 15 years with the introduction of many …

Drugs may cause serotonin toxicity by a number of different mechanisms including inhibition
of serotonin uptake and metabolism, increased serotonin synthesis and release, activation …

Tramadol is a cyclohexanol derivative with μ-agonist activity. It has been used as an
analgesic for postoperative or chronic pain since the late 1970s, and became one of the …