Sex-specific impact of maternal obesity on fetal placental macrophages and cord blood triglycerides
Introduction Maternal obesity is associated with increased risk of offspring obesity and
cardiometabolic disease. Altered fetoplacental immune programming is a potential …
cardiometabolic disease. Altered fetoplacental immune programming is a potential …
Maternal lipid levels across pregnancy impact the umbilical cord blood lipidome and infant birth weight
JL LaBarre, M Puttabyatappa, PXK Song… - Scientific reports, 2020 - nature.com
Major alterations in metabolism occur during pregnancy enabling the mother to provide
adequate nutrients to support infant development, affecting birth weight (BW) and potentially …
adequate nutrients to support infant development, affecting birth weight (BW) and potentially …
Maternal obesity alters placental lysophosphatidylcholines, lipid storage, and the expression of genes associated with lipid metabolism
Dyslipidemia is a characteristic of maternal obesity and previous studies have demonstrated
abnormalities in fatty acid oxidation and storage in term placentas. However, there is little …
abnormalities in fatty acid oxidation and storage in term placentas. However, there is little …
Placental lipid transport and content in response to maternal overweight and gestational diabetes mellitus in human term placenta
L Song, N Wang, Y Peng, B Sun, W Cui - Nutrition, Metabolism and …, 2022 - Elsevier
Background and aims Placental lipid transport is altered in women with high prepregnancy
body mass index (pre-BMI) or gestational diabetes (GDM), which consequently affects foetal …
body mass index (pre-BMI) or gestational diabetes (GDM), which consequently affects foetal …
Modulation of fatty acid transport and metabolism by maternal obesity in the human full-term placenta
E Dubé, A Gravel, C Martin, G Desparois… - Biology of …, 2012 - academic.oup.com
Abstract Knowledge of the consequences of maternal obesity in human placental fatty acids
(FA) transport and metabolism is limited. Animal studies suggest that placental uptake of …
(FA) transport and metabolism is limited. Animal studies suggest that placental uptake of …
[HTML][HTML] The pathologic changes of human placental macrophages in women with hyperglycemia in pregnancy
J Ning, M Zhang, D Cui, H Yang - Placenta, 2022 - Elsevier
As the most common complication of pregnancy, hyperglycemia has a profound impact on
maternal and fetal health and the long-term development of the offspring. Placental …
maternal and fetal health and the long-term development of the offspring. Placental …
Feto-placental adaptations to maternal obesity in the baboon
D Farley, ME Tejero, AG Comuzzie, PB Higgins, L Cox… - Placenta, 2009 - Elsevier
Maternal obesity is present in 20–34% of pregnant women and has been associated with
both intrauterine growth restriction and large-for-gestational age fetuses. While fetal and …
both intrauterine growth restriction and large-for-gestational age fetuses. While fetal and …
Obesity and maternal-placental-fetal immunology and health
M Monaco-Brown, DA Lawrence - Frontiers in pediatrics, 2022 - frontiersin.org
Obesity rates in women of childbearing age is now at 29%, according to recent CDC reports.
It is known that obesity is associated with oxidative stress and inflammation, including …
It is known that obesity is associated with oxidative stress and inflammation, including …
Maternal blood lipid profile during pregnancy and associations with child adiposity: findings from the ROLO study
AA Geraghty, G Alberdi, EJ O'Sullivan, EC O'Brien… - PloS one, 2016 - journals.plos.org
Background The in-utero environment affects fetal development; it is vital to understand how
maternal diet during pregnancy influences childhood body composition. While research …
maternal diet during pregnancy influences childhood body composition. While research …
Obesity in pregnancy stimulates macrophage accumulation and inflammation in the placenta
JC Challier, S Basu, T Bintein, J Minium, K Hotmire… - Placenta, 2008 - Elsevier
Obesity and pregnancy are associated with a combination of insulin resistance and
inflammatory changes which exacerbate in combination. Based on the similarity between …
inflammatory changes which exacerbate in combination. Based on the similarity between …