Methods and apparatus are provided for intravascularly-induced neuromodulation or
denervation. Neuromodulation may be achieved via direct and/or via indirect application of …

The present invention is an apparatus for pulsed electric field neuromodulation via an intra-
to-extravascular approach. The apparatus includes a pulsed electric field generator and at …

Methods and apparatus are provided for intravascularly-induced neuromodulation using a
pulsed electric field, eg, to effectuate irreversible electroporation or electrofusion, necrosis …

Methods and apparatus are provided for intravascularly-in duced neuromodulation using a
pulsed electric? eld, eg, to effectuate irreversible electroporation or electrofusion, necrosis …

Catheter apparatuses, systems, and methods for achieving renal neuromodulation by
intravascular access are disclosed herein. One aspect of the present application, for …

Catheter apparatuses, systems, and methods for achieving renal neuromodulation by
intravascular access are disclosed herein. One aspect of the present application, for …

Abstract Systems for nerve modulation through the wall of a blood vessel are disclosed. An
example system for nerve modulation may include an elongate member extending along a …

Methods and apparatus are provided for selective destruction or temporary disruption of
nerves and/or conduction pathways in a mammalian body for the treatment of pain and other …

Methods and apparatus are provided for treating acute myocardial infarction, eg, via a
pulsed electric field, via a stimulation electric field, via localized drug delivery, via high …

(65) Prior Publication Data OTHER PUBLICATIONS US 2007/0255379 A1 Nov. 1, 2007
Peters et al. The Evolution Strategy—A Search Strategy Used in• us Individual Optimization …