[HTML][HTML] Identification of lactate-related gene signature for prediction of progression and immunotherapeutic response in skin cutaneous melanoma

Y Xie, J Zhang, M Li, Y Zhang, Q Li, Y Zheng… - Frontiers in …, 2022 - frontiersin.org
Skin cutaneous melanoma (SKCM) is a skin cancer type characterized by a high degree of
immune cell infiltration. The potential function of lactate, a main metabolic product in the …

[HTML][HTML] Integrative lactylation and tumor microenvironment signature as prognostic and therapeutic biomarkers in skin cutaneous melanoma

Y Zhu, B Song, Z Yang, Y Peng, Z Cui, L Chen… - Journal of Cancer …, 2023 - Springer
Background The incidence of skin cutaneous melanoma (SKCM), one of the most
aggressive and lethal skin tumors, is increasing worldwide. However, for advanced SKCM …

Development and validation of an immune gene set-based prognostic signature in cutaneous melanoma

Q Tian, H Gao, W Zhao, Y Zhou, J Yang - Future Oncology, 2021 - Taylor & Francis
We aimed to fully understand the landscape of the skin cutaneous melanoma (SKCM)
microenvironment and develop an immune prognostic signature that can predict the …

Identification of immune-related genes with prognostic significance in the microenvironment of cutaneous melanoma

Y Qu, S Zhang, Y Zhang, X Feng, F Wang - Virchows Archiv, 2021 - Springer
Cutaneous melanoma is one of the most aggressive cancers characterized by increasing
incidence and mortality. In recent years, the emergence of immunotherapy has greatly …

[HTML][HTML] Analysis of immune subtypes based on immunogenomic profiling identifies prognostic signature for cutaneous melanoma

B Hu, Q Wei, C Zhou, M Ju, L Wang, L Chen, Z Li… - International …, 2020 - Elsevier
Skin cutaneous melanoma (SKCM) is the most invasive form of skin cancer with poor
prognosis. Growing evidence has demonstrated that tumor immune microenvironment plays …

[HTML][HTML] Transcriptome profiles of fatty acid metabolism-related genes and immune infiltrates identify hot tumors for immunotherapy in cutaneous melanoma

Y Dong, Z Zhao, M Simayi, C Chen, Z Xu, D Lv… - Frontiers in …, 2022 - frontiersin.org
Background: Immunotherapy with checkpoint inhibitors usually has a low response rate in
some cutaneous melanoma (CM) cases due to its cold nature. Hence, identification of hot …

[HTML][HTML] The fatty acid-related gene signature stratifies poor prognosis patients and characterizes TIME in cutaneous melanoma

S Hua, W Wang, Z Yao, J Gu, H Zhang, J Zhu… - Journal of Cancer …, 2024 - Springer
Background The aim of this study is to build a prognostic model for cutaneous melanoma
(CM) using fatty acid-related genes and evaluate its capacity for predicting prognosis …

[HTML][HTML] A novel prognostic model for cutaneous melanoma based on an immune-related gene signature and clinical variables

Y Tang, H Feng, L Zhang, C Qu, J Li, X Deng… - Scientific Reports, 2022 - nature.com
Abundant evidence has indicated that the prognosis of cutaneous melanoma (CM) patients
is highly complicated by the tumour immune microenvironment. We retrieved the clinical …

[HTML][HTML] Identification of novel molecular therapeutic targets and their potential prognostic biomarkers based on cytolytic activity in skin cutaneous melanoma

H Zhang, Y Liu, D Hu, S Liu - Frontiers in Oncology, 2022 - frontiersin.org
Skin cutaneous melanoma (SKCM) attracts attention worldwide for its extremely high
malignancy. A novel term cytolytic activity (CYT) has been introduced as a potential …

[HTML][HTML] C1QA, C1QB, and GZMB are novel prognostic biomarkers of skin cutaneous melanoma relating tumor microenvironment

Z Liang, L Pan, J Shi, L Zhang - Scientific reports, 2022 - nature.com
Skin cutaneous melanoma (SKCM) is the most lethal form of skin cancers owing to high
invasiveness and high metastatic potential. Tumor microenvironment (TME) provides …