Collagen provides mechanical and biological support for virtually all human tissues in the
extracellular matrix (ECM). Its defining molecular structure, the triple-helix, could be …

Collagen is a ubiquitous biomaterial in vertebrate animals. Although each of its 28 subtypes
contributes to the functions of many different tissues in the body, most studies on collagen or …

About this series The series Topics in Current Chemistry presents critical reviews of the
present and future trends in modern chemical research. The scope of coverage includes all …

Collagen is the oldest and most abundant extracellular matrix protein that has found many
applications in food, cosmetic, pharmaceutical, and biomedical industries. First, an overview …

Fibrillar collagens represent the most abundant extracellular matrix proteins in vertebrates
providing tissues and organs with form, stability, and connectivity. For such mechanical …

The picture emerging from recent discoveries about collagens, other matrix macromolecules
and their modes of organization is one of a complex modular system operating at all levels …

Collagen is the primary protein component in mammalian connective tissues. Over the last
20 years, evidence has mounted that collagen matrices exhibit substantial heterogeneity in …

Collagens are distinguished from other extracellular matrix proteins by their triple-helical
conformation. Triple-helical conformation has been proposed to be important for cellular …

Collagen is the most abundant protein in mammals, accounting for approximately one-third
of the total protein in the human body. Thus, it is a logical choice for the creation of …

The number of proteins known to contain collagen-like triple helical domains is rapidly
increasing. The functions of these domains are to provide molecular rods that separate …