[HTML][HTML] SAGA is a general cofactor for RNA polymerase II transcription

T Baptista, S Grünberg, N Minoungou, MJE Koster… - Molecular cell, 2017 - cell.com
Prior studies suggested that SAGA and TFIID are alternative factors that promote RNA
polymerase II transcription, with about 10% of genes in S. cerevisiae dependent on SAGA …

The Spt components of SAGA facilitate TBP binding to a promoter at a post-activator-binding step in vivo

AM Dudley, C Rougeulle, F Winston - Genes & development, 1999 - genesdev.cshlp.org
The SAGA complex of Saccharomyces cerevisiae is required for the transcription of many
RNA polymerase II-dependent genes. Previous studies have demonstrated that SAGA …

Differential requirement of SAGA components for recruitment of TATA-box-binding protein to promoters in vivo

SR Bhaumik, MR Green - Molecular and cellular biology, 2002 - Taylor & Francis
The multisubunit Saccharomyces cerevisiae SAGA (Spt-Ada-Gcn5-acetyltransferase)
complex is required to activate transcription of a subset of RNA polymerase II-dependent …

Architecture of the Saccharomyces cerevisiae SAGA transcription coactivator complex

Y Han, J Luo, J Ranish, S Hahn - The EMBO journal, 2014 - embopress.org
The conserved transcription coactivator SAGA is comprised of several modules that are
involved in activator binding, TBP binding, histone acetylation (HAT) and deubiquitination …

[HTML][HTML] Transcription of nearly all yeast RNA polymerase II-transcribed genes is dependent on transcription factor TFIID

L Warfield, S Ramachandran, T Baptista, D Devys… - Molecular cell, 2017 - cell.com
Previous studies suggested that expression of most yeast mRNAs is dominated by either
transcription factor TFIID or SAGA. We re-examined the role of TFIID by rapid depletion of S …

[HTML][HTML] Molecular architecture of the S. cerevisiae SAGA complex

PYJ Wu, C Ruhlmann, F Winston, P Schultz - Molecular cell, 2004 - cell.com
The Saccharomyces cerevisiae SAGA complex is a multifunctional coactivator that regulates
transcription by RNA polymerase II. The 3D structure of SAGA, revealed by electron …

[HTML][HTML] Two roles for the yeast transcription coactivator SAGA and a set of genes redundantly regulated by TFIID and SAGA

R Donczew, L Warfield, D Pacheco, A Erijman, S Hahn - Elife, 2020 - elifesciences.org
Deletions within genes coding for subunits of the transcription coactivator SAGA caused
strong genome-wide defects in transcription and SAGA-mediated chromatin modifications. In …

What do transcription factors interact with?

H Chen, BF Pugh - Journal of molecular biology, 2021 - Elsevier
Although we have made significant progress, we still possess a limited understanding of
how genomic and epigenomic information directs gene expression programs through …

Essential Functional Interactions of SAGA, a Saccharomyces cerevisiae Complex of Spt, Ada, and Gcn5 Proteins, With the Snf/Swi and Srb/Mediator Complexes

SM Roberts, F Winston - Genetics, 1997 - academic.oup.com
The Saccharomyces cerevisiae transcription factor Spt20/Ada5 was originally identified by
mutations that suppress Ty insertion alleles and by mutations that suppress the toxicity …

Cluster analysis of mass spectrometry data reveals a novel component of SAGA

DW Powell, CM Weaver, JL Jennings… - … and cellular biology, 2004 - Taylor & Francis
The SAGA histone acetyltransferase and TFIID complexes play key roles in eukaryotic
transcription. Using hierarchical cluster analysis of mass spectrometry data to identify …