[HTML][HTML] Urban PM2.5 exacerbates allergic inflammation in the murine lung via a TLR2/TLR4/MyD88-signaling pathway

M He, T Ichinose, Y Yoshida, K Arashidani… - Scientific reports, 2017 - nature.com
Nevertheless its mechanism has not been well explained yet, PM2. 5 is recognized to
exacerbate asthma. In the present study, the roles of toll-like receptor (TLR) 2, TLR4 and …

PM2. 5 exposure regulates Th1/Th2/Th17 cytokine production through NF-κB signaling in combined allergic rhinitis and asthma syndrome

CH Piao, Y Fan, T Van Nguyen, CH Song… - International …, 2023 - Elsevier
Background Particulate matter (PM) is a major component of air pollution from emissions
from anthropogenic and natural sources and is a serious problem worldwide due to its …

Ambient PM2. 5 exposure exacerbates severity of allergic asthma in previously sensitized mice

X Zhang, W Zhong, Q Meng, Q Lin, C Fang… - Journal of …, 2015 - Taylor & Francis
Objective: Epidemiological studies have shown that elevated concentrations of ambient
particulate matter (aerodynamic diameter≤ 2.5 μm; PM2. 5) correlates with increased …

PM2. 5-rich dust collected from the air in Fukuoka, Kyushu, Japan, can exacerbate murine lung eosinophilia

M He, T Ichinose, Y Ren, Y Song, Y Yoshida… - Inhalation …, 2015 - Taylor & Francis
Abstract PM2. 5 can exacerbate asthma. Organic substances adsorbed on PM2. 5-rich dust
(PM2. 5rd) were inactivated by heating at 360° C. To characterize the role of organic …

Continuous exposure of PM2. 5 exacerbates ovalbumin-induced asthma in mouse lung via a JAK-STAT6 signaling pathway.

Y Yang, X Li, X An, L Zhang, X Li… - Advances in Clinical …, 2020 - search.ebscohost.com
Background: Epidemiological studies and mice models have demonstrated that air pollution
containing particulate matter smaller than 2.5 µm (PM2. 5) exacerbates acute episodes of …

Desert dust induces TLR signaling to trigger Th2-dominant lung allergic inflammation via a MyD88-dependent signaling pathway

M He, T Ichinose, Y Song, Y Yoshida, K Bekki… - Toxicology and applied …, 2016 - Elsevier
Asian sand dust (ASD) is known to exacerbate asthma, although its mechanism is not yet
well understood. In this study, when the effects on inflammatory response by LPS present in …

Toll-like receptor 2 down-regulation in established mouse allergic lungs contributes to decreased mycoplasma clearance

Q Wu, RJ Martin, S LaFasto, BJ Efaw… - American journal of …, 2008 - atsjournals.org
Rationale: Respiratory Mycoplasma pneumoniae (Mp) infection is involved in asthma
pathobiology, but whether the established allergic airway inflammation compromises lung …

[HTML][HTML] Lipoxin A4 regulates PM2. 5-induced severe allergic asthma in mice via the Th1/Th2 balance of group 2 innate lymphoid cells

X Lu, H Fu, F Han, Y Fang, J Xu, L Zhang… - Journal of thoracic …, 2018 - ncbi.nlm.nih.gov
Background Urban particulate matter (PM) contributes to the increasing number of people
with asthma, which is closely related to the development of industrialization. Especially, PM …

[HTML][HTML] The acute airway inflammation induced by PM2.5 exposure and the treatment of essential oils in Balb/c mice

H Wang, L Song, W Ju, X Wang, L Dong, Y Zhang… - Scientific Reports, 2017 - nature.com
PM2. 5 is the main particulate air pollutant whose aerodynamic diameter is less than 2.5
micron. The inflammation of various respiratory diseases are associated with PM2. 5 …

[HTML][HTML] TLR4/MyD88-induced CD11b+ Gr-1intF4/80+ non-migratory myeloid cells suppress Th2 effector function in the lung

M Arora, SL Poe, TB Oriss, N Krishnamoorthy… - Mucosal …, 2010 - Elsevier
In humans, environmental exposure to a high dose of lipopolysaccharide (LPS) protects
from allergic asthma, the immunological underpinnings of which are not well understood. In …