Motor function and anxiety-like responses are easily quantifiable in zebrafish, a novel model
organism for behavioral pharmacology. Activation of serotonin receptors through the use of …

Due to the fish-specific genome duplication event (~ 320–350 mya), some genes which
code for serotonin proteins were duplicated in teleosts; this duplication event was preceded …

Serotonin (5-HT) is a neurotransmitter that is involved in many behavioral functions,
including the organization of defense, and its putative pathological correlate, anxiety and …

The action of anxiolytic compounds that act on selective serotonin receptors (SSRIs) have
been scarcely evaluated. Serotonergic drugs have been shown to be effective in treating …

Serotonin syndrome (SS) is a serious life-threatening disorder associated with elevated
brain serotonergic function. With the growing use of serotonergic drugs, SS affects a large …

The discovery that selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine are
present and bioaccumulate in aquatic ecosystems have spurred studies of fish serotonin …

Variation among individuals may arise for several reasons, and may have diverse
underlying mechanisms. Individual differences have been studied in a variety of species, but …

Current theories on the role of serotonin (5‐HT) in vertebrate defensive behavior suggest
that this monoamine increases anxiety but decreases fear, by acting at different levels of the …

Zebrafish (Danio rerio) have emerged as a popular model for studying the pharmacology
and behavior of anxiety. While there have been numerous studies documenting the …

Zebrafish, Danio rerio, is an emerging model organism in stress and neurobehavioral
studies. In nature, the species forms shoals, yet when kept in pairs it exhibits an agonistic …