Non-muscle myosin II takes centre stage in cell adhesion and migration
M Vicente-Manzanares, X Ma, RS Adelstein… - … reviews Molecular cell …, 2009 - nature.com
Non-muscle myosin II (NM II) is an actin-binding protein that has actin cross-linking and
contractile properties and is regulated by the phosphorylation of its light and heavy chains …
contractile properties and is regulated by the phosphorylation of its light and heavy chains …
Nonmuscle myosin II isoform and domain specificity during early mouse development
A Wang, X Ma, MA Conti, C Liu… - Proceedings of the …, 2010 - National Acad Sciences
Nonmuscle myosins (NMs) II-A and II-B are essential for embryonic mouse development, but
their specific roles are not completely defined. Here we examine the isoforms and their …
their specific roles are not completely defined. Here we examine the isoforms and their …
Nonmuscle myosin II moves in new directions
MA Conti, RS Adelstein - Journal of cell science, 2008 - journals.biologists.com
For many years, analyses of the role of the actomyosin cytoskeleton in many basic cellular
processes have centered on actin. Increasingly, however, a number of investigators are …
processes have centered on actin. Increasingly, however, a number of investigators are …
Nonmuscle myosin II isoforms coassemble in living cells
Summary Nonmuscle myosin II (NM II) powers myriad developmental and cellular
processes, including embryogenesis, cell migration, and cytokinesis [1]. To exert its …
processes, including embryogenesis, cell migration, and cytokinesis [1]. To exert its …
Endogenous species of mammalian nonmuscle myosin IIA and IIB include activated monomers and heteropolymers
MS Shutova, WA Spessott, CG Giraudo, T Svitkina - Current Biology, 2014 - cell.com
Background Class II myosins generate contractile forces in cells by polymerizing into bipolar
filaments and pulling on anchored actin filaments. Nonmuscle myosin II (NMII) plays central …
filaments and pulling on anchored actin filaments. Nonmuscle myosin II (NMII) plays central …
Nonmuscle myosin II regulation directs its multiple roles in cell migration and division
M Garrido-Casado, G Asensio-Juárez… - Annual review of cell …, 2021 - annualreviews.org
Nonmuscle myosin II (NMII) is a multimeric protein complex that generates most mechanical
force in eukaryotic cells. NMII function is controlled at three main levels. The first level …
force in eukaryotic cells. NMII function is controlled at three main levels. The first level …
Myosin II isoforms play distinct roles in adherens junction biogenesis
Adherens junction (AJ) assembly under force is essential for many biological processes like
epithelial monolayer bending, collective cell migration, cell extrusion and wound healing …
epithelial monolayer bending, collective cell migration, cell extrusion and wound healing …
Non-muscle myosin II in disease: mechanisms and therapeutic opportunities
KA Newell-Litwa, R Horwitz… - Disease models & …, 2015 - journals.biologists.com
The actin motor protein non-muscle myosin II (NMII) acts as a master regulator of cell
morphology, with a role in several essential cellular processes, including cell migration and …
morphology, with a role in several essential cellular processes, including cell migration and …
Characterization of three full-length human nonmuscle myosin II paralogs
N Billington, A Wang, J Mao, RS Adelstein… - Journal of Biological …, 2013 - ASBMB
Nonmuscle myosin IIs (NM IIs) are a group of molecular motors involved in a wide variety of
cellular processes including cytokinesis, migration, and control of cell morphology. There …
cellular processes including cytokinesis, migration, and control of cell morphology. There …
Nonmuscle myosin IIA-dependent force inhibits cell spreading and drives F-actin flow
Y Cai, N Biais, G Giannone, M Tanase, G Jiang… - Biophysical journal, 2006 - cell.com
Abstract Nonmuscle myosin IIA (NMM-IIA) is involved in the formation of focal adhesions and
neurite retraction. However, the role of NMM-IIA in these functions remains largely unknown …
neurite retraction. However, the role of NMM-IIA in these functions remains largely unknown …