Autoantibodies to neuronal antigens in children with new‐onset seizures classified according to the revised ILAE organization of seizures and epilepsies

J Suleiman, S Wright, D Gill, F Brilot, P Waters… - …, 2013 - Wiley Online Library
Purpose Potentially pathogenic autoantibodies are found increasingly in adults with seizure
disorders, including focal seizures and those of unknown cause. In this study, we …

Autoantibodies to neuronal antigens in children with focal epilepsy and no prima facie signs of encephalitis

P Borusiak, U Bettendorf, G Wiegand, T Bast… - european journal of …, 2016 - Elsevier
Objective There is increasing awareness of neuronal autoantibodies and their impact on the
pathogenesis of epilepsy. We investigated children with focal epilepsy in order to provide an …

Neuronal antibodies in pediatric epilepsy: clinical features and long‐term outcomes of a historical cohort not treated with immunotherapy

S Wright, AT Geerts, CM Jol‐van der Zijde… - …, 2016 - Wiley Online Library
Objective In autoimmune encephalitis the etiologic role of neuronal cell‐surface antibodies
is clear; patients diagnosed and treated early have better outcomes. Neuronal antibodies …

Antibodies contributing to focal epilepsy signs and symptoms score

MAAM de Bruijn, AEM Bastiaansen… - Annals of …, 2021 - Wiley Online Library
Objective Diagnosing autoimmune encephalitis (AIE) is difficult in patients with less
fulminant diseases such as epilepsy. However, recognition is important, as patients require …

Prevalence of neurologic autoantibodies in cohorts of patients with new and established epilepsy

T Brenner, GJ Sills, Y Hart, S Howell, P Waters… - …, 2013 - Wiley Online Library
Purpose Autoantibodies to specific neurologic proteins are associated with subacute onset
encephalopathies, which often present with seizures that are poorly controlled by …

[HTML][HTML] Seizures associated with antibodies against cell surface antigens are acute symptomatic and not indicative of epilepsy: insights from long-term data

A Rada, R Birnbacher, C Gobbi, M Kurthen… - Journal of …, 2021 - Springer
Background Clinicians have questioned whether any disorder involving seizures and neural
antibodies should be called “(auto) immune epilepsy.” The concept of “acute symptomatic …

Discerning the role of autoimmunity and autoantibodies in epilepsy: a review

C Steriade, L Gillinder, K Rickett, G Hartel… - JAMA …, 2021 - jamanetwork.com
Importance The literature on neural autoantibody positivity in epilepsy has expanded over
the last decade, with an increased interest among clinicians in identifying potentially …

Autoimmune epilepsy in children: case series and proposed guidelines for identification

J Suleiman, F Brilot, B Lang, A Vincent, RC Dale - Epilepsia, 2013 - Wiley Online Library
Purpose Antibodies against neuronal surface proteins are increasingly recognized in
autoimmune central nervous system (CNS) disorders in which seizures are the main or an …

Neuronal antibody prevalence in children with seizures under 3 years: a prospective national cohort

JD Symonds, TC Moloney, B Lang, A McLellan… - Neurology, 2020 - AAN Enterprises
Objective To report the prevalence of anti-neuronal antibodies in a prospective whole-nation
cohort of children presenting with seizures before their third birthday. Methods This was a …

[HTML][HTML] Prevalence of neural autoantibodies in epilepsy of unknown etiology: systematic review and meta-analysis

P Cabezudo-García, N Mena-Vázquez… - Brain Sciences, 2021 - mdpi.com
Background: The prevalence of neural autoantibodies in epilepsy of unknown etiology
varies among studies. We aimed to conduct a systematic review and meta-analysis to …