The role of Igs in natural protection against infection by Mycobacterium tuberculosis (Mtb),
the causative agent of TB, is controversial. Although passive immunization with mAbs …

Accumulating evidence from experimental animal models suggests that antibodies play a
protective role against tuberculosis (TB). However, little is known about the antibodies …

Better understanding of the immunological components and their interactions necessary to
prevent or control Mycobacterium tuberculosis (Mtb) infection in humans is critical for …

Are antibodies important for protection against tuberculosis? The jury has been out for more
than 100 years. B cell depletion in experimental Mycobacterium tuberculosis infection failed …

Abstract Development of an effective tuberculosis (TB) vaccine has suffered from an
incomplete understanding of the correlates of protection against Mycobacterium tuberculosis …

The most common test to identify latent tuberculosis is the tuberculin skin test that detects T
cell responses of delayed type hypersensitivity type IV. Since it produces false negative …

Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is one of the most important
infectious diseases globally. Immune effector mechanisms that lead to protection or …

Protective immunity against infection with Mycobacterium tuberculosis is imparted by T cells
rather than antibodies, but B cells can play a role as antigen-presenting cells and in …

Rationale: Individuals with a history of tuberculosis (TB) disease are at elevated risk of
disease recurrence. The underlying cause is not known, but one explanation is that previous …

There is an urgent need for new and better vaccines against tuberculosis (TB). Current
vaccine design strategies are generally focused on the enhancement of cell-mediated …