Early prenatal diagnosis of fetal sex is necessary to optimize pregnancy management in
families known to be at risk of some heritable disorders. The demonstration of cell-free fetal …

Background Cell-free fetal DNA (cffDNA) can be detected in maternal blood during
pregnancy, opening the possibility of early non-invasive prenatal diagnosis for a variety of …

Prenatal fetal sex determination is undertaken in women at high risk of serious genetic
disorders affecting a specific sex. Traditionally, this is undertaken by invasive testing, usually …

Hill M, Finning K, Martin P, Hogg J, Meaney C, Norbury G, Daniels G, Chitty LS. Non‐
invasive prenatal determination of fetal sex: translating research into clinical practice. The …

OBJECTIVE: To determine the diagnostic accuracy of noninvasive fetal sex determination in
maternal plasma. METHODS: All consecutive patients for whom fetal sex determination in …

OBJECTIVE: Clinical indications for fetal sex determination include risk of X-linked
disorders, a family history of conditions associated with ambiguous development of the …

Objective This study reviews our clinical experience of non‐invasive techniques for early sex
determination. It assesses the effectiveness of these techniques at reducing invasive …

Non-invasive prenatal diagnosis is now a clinical reality, using both early ultrasound and
molecular DNA methods. Technical advances in the sensitivity of the polymerase chain …

Prenatal fetal sex determination is clinically indicated for women who are at risk of having a
child with a serious genetic disorder affecting a particular sex. Ultrasound has been the …

Nowadays, new advances in the use of cell free fetal DNA (cffDNA) in maternal plasma of
pregnant women has provided the possibility of applying cffDNA in prenatal diagnosis as a …