Often considered the “housekeeping” cells of the brain, astrocytes have of late been rising to
the forefront of neurodegenerative disorder research. Identified as crucial components of a …

The brain is composed of distinct neuronal and glial cell-types that require sophisticated
interactions and co-regulation to maintain healthy brain function. The cell-type specific …

Increasing evidence supports a pathogenic role of unabated neuroinflammation in various
central nervous system (CNS) diseases, including epilepsy. Neuroinflammation is not a …

Epilepsy, a neurological disorder characterized by recurring seizures, has long been a
subject of scientific exploration. Recent research has unveiled an intriguing link between …

Epilepsy is a brain disease associated with epileptic seizures as well as with
neurobehavioral outcomes of this condition. In the last century, inflammation emerged as a …

Neuroinflammation and epilepsy are interconnected. Brain inflammation promotes neuronal
hyper-excitability and seizures, and dysregulation in the glia immune-inflammatory function …

PREFACE Inflammation is a prototypical response to injury or infection. This homeostatic
mechanism is activated in the challenged tissue in order to reestablish homeostasis and …

Unabated neuroinflammation plays a pathogenic role in various CNS diseases. In epilepsy,
neuroinflammation is not a bystander phenomenon of the diseased brain but contributes to …

Multiple sclerosis (MS), the most common inflammatory condition of the central nervous
system in young adults, is characterized by immunemediated demyelination and …

Neurodevelopmental and neurodegenerative diseases including early-onset epilepsy,
dementia, and stroke are major challenges for modern medicine because their …