Bladder cancer, inflammageing and microbiomes

A Martin, BL Woolbright, S Umar, MA Ingersoll… - Nature Reviews …, 2022 - nature.com
Ageing is correlated with elevated bladder cancer incidence, morbidity and mortality.
Advanced age is also associated with elevated markers of chronic inflammation and …

The microbiome and genitourinary cancer: a collaborative review

MC Markowski, SA Boorjian, JP Burton, NM Hahn… - European urology, 2019 - Elsevier
Context The recent discovery of the existence of a human genitourinary microbiome has led
to the investigation of its role in mediating the pathogenesis of genitourinary malignancies …

Profiling the bladder microbiota in patients with bladder cancer

M Parra-Grande, M Oré-Arce… - Frontiers in …, 2022 - frontiersin.org
Evidence suggests that microbiota may contribute to the pathogenesis of several diseases,
including cancer. In the case of bladder cancer, preliminary studies have found alterations in …

Bladder cancer-related microbiota: examining differences in urine and tissue samples

B Mansour, Á Monyók, N Makra, M Gajdács… - Scientific Reports, 2020 - nature.com
The microbiota isolated from the urine of bladder carcinoma patients exhibits significantly
increased compositional abundance of some bacterial genera compared to the urine of …

[HTML][HTML] Mini-review: perspective of the microbiome in the pathogenesis of urothelial carcinoma

W Xu, L Yang, P Lee, WC Huang, C Nossa… - American journal of …, 2014 - ncbi.nlm.nih.gov
The microbiome is a new center of attention for studies on the pathogenesis of human
disease by focusing on the alterations of all microorganisms living in a particular site or …

Urinary microbiota and bladder cancer: A systematic review and a focus on uropathogens

A Yacouba, MT Alou, JC Lagier, G Dubourg… - Seminars in Cancer …, 2022 - Elsevier
The higher incidence of bladder cancer in men has long been attributed to environmental
factors, including smoking. The fact that the sex ratio of bladder cancer remains consistently …

The urinary microbiome: implications in bladder cancer pathogenesis and therapeutics

P Bajic, AJ Wolfe, GN Gupta - Urology, 2019 - Elsevier
Recent investigation has proven that the bladder is not sterile. However, the implications of
this finding in the pathophysiology and management of urothelial cell carcinoma have not …

The bladder is not sterile: an update on the urinary microbiome

AL Ackerman, TC Chai - Current bladder dysfunction reports, 2019 - Springer
Abstract Purpose of Review The article discusses (1) techniques used to study bacterial
urinary microbiota;(2) existence of non-bacterial urinary microbiota;(3) associations between …

The urinary tract microbiome in health and disease

IM Aragon, B Herrera-Imbroda, MI Queipo-Ortuño… - European urology …, 2018 - Elsevier
Context The urinary tract, previously considered a sterile body niche, has emerged as the
host of an array of bacteria in healthy individuals, revolutionizing the urology research field …

Effects of aging on urinary tract epithelial homeostasis and immunity

MM Ligon, CS Joshi, BE Fashemi, AM Salazar… - Developmental …, 2023 - Elsevier
A global increase in older individuals creates an increasing demand to understand
numerous healthcare challenges related to aging. This population is subject to changes in …