Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease with a very poor prognosis as it
has a 2.5 to 5 years mean survival after proper diagnosis. Even nintedanib and pirfenidone …

Aims Idiopathic pulmonary fibrosis (IPF) is a severe pulmonary interstitial pneumonia. Our
study focuses on the role of PLA2 enzyme in the IPF to explore a more effective diagnosis …

Inffammation of the lung marked by excessive recruitment of neutrophils from circulation to
the airway is a common feature among several pathological lung disorders, particularly …

Phospholipase A2 (PLA2) is a growing family of enzymes that may play a major role in
inflammation. We investigated the effect of tumor necrosis factor-α (TNF-α) and interferon-γ …

The mechanism of bleomycin (Bleo)-induced pulmonary injury is not fully understood.
Elevated levels of lung phospholipase A2 (PLA2) have been previously reported following …

Background: The Gly80Ser polymorphism in phospholipase A2-IID (PLA2G2D, NCBI SNP
reference: rs584367) is associated with a loss in body weight in patients with chronic …

Abstract Phospholipase A 2 (PLA 2) is a superfamily of enzymes that may play a major role
in airways inflammation. We investigated the effect of interferon-γ (IFN-γ) on the gene …

Damage and activation of lung endothelium can lead to interstitial edema, infiltration of
inflammatory cells into the interstitium and airways, and production of inflammatory …

Pulmonary fibrosis is an interstitial disorder of the lung parenchyma whose mechanism is
poorly understood. Potential mechanisms include the infiltration of inflammatory cells to the …

Pulmonary fibrosis (PF) is the pathological change of end-stage interstitial lung diseases
with high mortality and limited therapeutic options. Lung macrophages have distinct subsets …