Genomic insights on heterogeneous resistance to vancomycin and teicoplanin in Methicillin-resistant Staphylococcus aureus: A first report from South India

YD Bakthavatchalam, P Babu, E Munusamy… - PLoS …, 2019 - journals.plos.org
Methicillin-resistant Staphylococcus aureus (MRSA) infection is an important clinical
concern in patients, and is often associated with significant disease burden and metastatic …

Molecular Events for Promotion of Vancomycin Resistance in Vancomycin Intermediate Staphylococcus aureus

Q Hu, H Peng, X Rao - Frontiers in microbiology, 2016 - frontiersin.org
Vancomycin has been used as the last resort in the clinical treatment of serious
Staphylococcus aureus infections. Vancomycin-intermediate S. aureus (VISA) was …

[HTML][HTML] A novel mutation of walK confers vancomycin-intermediate resistance in methicillin-susceptible Staphylococcus aureus

J Zhu, B Liu, X Shu, B Sun - International Journal of Medical Microbiology, 2021 - Elsevier
With the treatment failure by vancomycin and poor clinical outcomes, the emergence and
spread of vancomycin intermediate-resistant Staphylococcus aureus (VISA) has raised more …

Genetic alterations in methicillin-susceptible Staphylococcus aureus associated with high vancomycin minimum inhibitory concentration

YR Kang, DR Chung, JH Ko, K Huh, SY Cho… - International Journal of …, 2023 - Elsevier
Background There are many reports on gene mutations observed in methicillin-resistant
Staphylococcus aureus (MRSA) showing reduced susceptibility to vancomycin. However …

Phenotypic and genomic comparisons of highly vancomycin-resistant Staphylococcus aureus strains developed from multiple clinical MRSA strains by in vitro …

K Ishii, F Tabuchi, M Matsuo, K Tatsuno, T Sato… - Scientific reports, 2015 - nature.com
The development of vancomycin (VCM) resistance in Staphylococcus aureus threatens
global health. Studies of the VCM-resistance mechanism and alternative therapeutic …

Novel Mutation Sites in the Development of Vancomycin- Intermediate Resistance in Staphylococcus aureus

Y Wang, X Li, L Jiang, W Han, X Xie, Y Jin… - Frontiers in …, 2017 - frontiersin.org
Increased use of vancomycin has led to the emergence of vancomycin-intermediate
Staphylococcus aureus (VISA). To investigate the mechanism of VISA development, 39 …

Emergence of vancomycin-intermediate and-resistant Staphylococcus aureus among methicillin-resistant S. aureus isolated from clinical specimens in the northwest …

M Ghahremani, NH Jazani, Y Sharifi - Journal of global antimicrobial …, 2018 - Elsevier
Objectives The aim of this study was to evaluate the frequency as well as the phenotypic and
molecular characteristics of methicillin-resistant Staphylococcus aureus (MRSA) and …

Contribution of selected gene mutations to resistance in clinical isolates of vancomycin-intermediate Staphylococcus aureus

C Hafer, Y Lin, J Kornblum, FD Lowy… - Antimicrobial agents …, 2012 - Am Soc Microbiol
Infections with vancomycin-intermediate Staphylococcus aureus (VISA) have been
associated with vancomycin treatment failures and poor clinical outcomes. Routine …

Novel single-nucleotide variations associated with vancomycin resistance in vancomycin-intermediate Staphylococcus aureus

LC Lin, SC Chang, MC Ge, TP Liu… - Infection and drug …, 2018 - Taylor & Francis
Prolonged vancomycin usage may cause methicillin-resistant Staphylococcus aureus to
become vancomycin-intermediate S. aureus (VISA) and heterogeneous VISA (hVISA) …

Comparative genomics identifies novel genetic changes associated with oxacillin, vancomycin and daptomycin susceptibility in ST100 methicillin-resistant …

S Di Gregorio, MS Haim, ÁMR Famiglietti, J Di Conza… - Antibiotics, 2023 - mdpi.com
Infections due to vancomycin-intermediate S. aureus (VISA) and heterogeneous VISA
(hVISA) represent a serious concern due to their association with vancomycin treatment …