Antigen processing defects in cervical carcinomas limit the presentation of a CTL epitope from human papillomavirus 16 E6
M Evans, LK Borysiewicz, AS Evans… - The Journal of …, 2001 - journals.aai.org
Human papillomavirus (HPV) infection, particularly type 16, is causally associated with the
development of cervical cancer. The E6 and E7 proteins of HPV are constitutively expressed …
development of cervical cancer. The E6 and E7 proteins of HPV are constitutively expressed …
Cross‐typic specificity and immunotherapeutic potential of a human HPV16 E7‐specific CTL line
SJ Youde, CM McCarthy, KJ Thomas… - … Journal of Cancer, 2005 - Wiley Online Library
Cervical cancer (CaCx) is strongly associated with human papillomavirus (HPV) infection,
particularly HPV types 16 and 18. The constitutive expression of HPV E6 and E7 proteins in …
particularly HPV types 16 and 18. The constitutive expression of HPV E6 and E7 proteins in …
Paucity of functional CTL epitopes in the E7 oncoprotein of cervical cancer associated human papillomavirus type 16
V Khammanivong, XS Liu, WJ Liu… - Immunology and cell …, 2003 - Wiley Online Library
Many specific antiviral and antitumour immune responses have been attributed to the
protective effects of antigen‐specific CD8+ cytotoxic T lymphocytes (CTL). Recognition of …
protective effects of antigen‐specific CD8+ cytotoxic T lymphocytes (CTL). Recognition of …
Occasional memory cytotoxic T-cell responses of patients with human papillomavirus type 16-positive cervical lesions against a human leukocyte antigen-A* 0201 …
ME Ressing, WJ van Driel, E Celis, A Sette… - Cancer Research, 1996 - AACR
Most cervical carcinoma (Cxca) cells constitutively express human papillomavirus type 16
(HPV16) E6 and E7 oncoproteins. These proteins are, therefore, attractive targets for T cell …
(HPV16) E6 and E7 oncoproteins. These proteins are, therefore, attractive targets for T cell …
CD4+ tumor-infiltrating lymphocytes in cervical cancer recognize HLA-DR-restricted peptides provided by human papillomavirus-E7
H Höhn, H Pilch, S Gunzel, C Neukirch… - The Journal of …, 1999 - journals.aai.org
Human papillomavirus (HPV)-encoded proteins may provide targets for CD8+ or CD4+ T
lymphocytes infiltrating into cervical cancer. We established an MHC class II-restricted CD4+ …
lymphocytes infiltrating into cervical cancer. We established an MHC class II-restricted CD4+ …
Identification of an HLA‐A24‐restricted cytotoxic T lymphocyte epitope from human papillomavirus type‐16 E6: The combined effects of bortezomib and interferon‐γ …
S Morishima, Y Akatsuka, A Nawa… - … journal of cancer, 2007 - Wiley Online Library
About 50% of cervical cancers are associated with human papillomavirus type 16 (HPV‐16),
and since the HPV‐16 E6 and E7 oncoproteins are constitutively expressed in the tumor …
and since the HPV‐16 E6 and E7 oncoproteins are constitutively expressed in the tumor …
Human CTL epitopes encoded by human papillomavirus type 16 E6 and E7 identified through in vivo and in vitro immunogenicity studies of HLA-A* 0201-binding …
ME Ressing, A Sette, RM Brandt, J Ruppert… - … (Baltimore, Md.: 1950 …, 1995 - journals.aai.org
Abstract Human papillomavirus type 16 (HPV16) is strongly associated with cervical
carcinogenesis. The HPV16 E6 and E7 oncoproteins are constitutively expressed in the …
carcinogenesis. The HPV16 E6 and E7 oncoproteins are constitutively expressed in the …
In vitro generation and life span extension of human papillomavirus type 16-specific, healthy donor-derived CTL clones
MWJ Schreurs, KBJ Scholten, EWM Kueter… - The Journal of …, 2003 - journals.aai.org
Human papillomavirus (HPV) type 16 infection is strongly associated with the development
of cervical carcinoma (CxCa) in women. The HPV16-derived oncoproteins E6 and E7 …
of cervical carcinoma (CxCa) in women. The HPV16-derived oncoproteins E6 and E7 …
Human papillomavirus type 33 E7 peptides presented by HLA-DR* 0402 to tumor-infiltrating T cells in cervical cancer
H Höhn, H Pilch, S Günzel, C Neukirch… - Journal of …, 2000 - Am Soc Microbiol
Several characteristics make human papillomavirus (HPV) amenable to vaccination. Anti-
HPV-directed vaccines are based on the observation that HPV E6 and E7 oncoproteins are …
HPV-directed vaccines are based on the observation that HPV E6 and E7 oncoproteins are …
Human papillomavirus-specific cytotoxic T lymphocytes in patients with cervical intraepithelial neoplasia grade III
M Nimako, AN Fiander, GWG Wilkinson… - Cancer research, 1997 - AACR
Human papillomaviruses (HPVs), especially types 16 and 18, are strongly associated with
the development of cervical intraepithelial neoplasia (CIN) and invasive carcinoma. The …
the development of cervical intraepithelial neoplasia (CIN) and invasive carcinoma. The …