Cells of the innate and adaptive immune systems are the progeny of a variety of
haematopoietic precursors, the most primitive of which is the haematopoietic stem cell …

Hematopoietic stem cells (HSCs) are the progenitors of all blood and immune cells, yet their
role in immunity is not well understood. Most studies have focused on the ability of …

Hematopoietic stem cells (HSCs) are quiescent cells with self-renewal capacity and the
ability to generate all mature blood cells. HSCs normally reside in specialized niches in the …

Lifelong blood production is maintained by bone marrow (BM)-residing hematopoietic stem
cells (HSCs) that are defined by two special properties: multipotency and self-renewal. Since …

Hematopoietic stem cells (HSC) reside in the bone marrow (BM) within a specialized micro-
environment, the HSC niche, which comprises several cellular constituents. These include …

Hematopoietic stem cells (HSCs) are a rare population that gives rise to almost all cells of
the hematopoietic system, including immune cells. Until recently, it was thought that immune …

Hematopoietic stem cells (HSCs) are a rare subset of bone marrow cells that usually exist in
a quiescent state, only entering the cell cycle to replenish the blood compartment, thereby …

Hematopoiesis is hierarchically orchestrated by a very small population of hematopoietic
stem cells (HSCs) that reside in the bone-marrow niche and are tightly regulated to maintain …

Hematopoiesis is the hierarchical process in which all lineages of blood cells are produced
by self-renewing hematopoietic stem cells (HSCs) in the bone marrow (BM). While the …

Inflammation is an evolutionarily selected defense response to infection or tissue damage
that involves activation and consumption of immune cells in order to reestablish and …