Ischemic heart disease including myocardial infarction is still the leading cause of death
worldwide. Although the survival early after myocardial infarction has been significantly …

Myocardial infarction is a leading cause of death worldwide. Although advances have been
made in acute treatment, an incomplete understanding of remodelling processes has limited …

Spatially resolved multiomics is an emerging approach for profiling gene expression at the
cellular level while maintaining the spatial organization of tissues. Its application in healthy …

Cardiovascular diseases (CVDs) impose a significant burden worldwide. Despite the
elucidation of the etiology and underlying molecular mechanisms of CVDs by numerous …

We introduce Single-cell Nanopore Spatial Transcriptomics (scNaST), a software suite to
facilitate the analysis of spatial gene expression from second-and third-generation …

Spatial multi-omic studies have emerged as a promising approach to comprehensively
analyze cells in tissues, enabling the joint analysis of multiple data modalities like …

Cardiovascular disease is the leading cause of death globally. An advanced understanding
of cardiovascular disease mechanisms is required to improve therapeutic strategies and …

Understanding the spatial gene expression and regulation in the heart is key to uncovering
its developmental and physiological processes, during homeostasis and disease. Numerous …

Therapeutic angiogenesis represents a promising avenue to revascularize the ischemic
heart. Its limited success is partly due to our poor understanding of the cardiac stroma …

Current transcriptomics technologies, including bulk RNA-seq, single-cell RNA sequencing
(scRNA-seq), single-nucleus RNA-sequencing (snRNA-seq), and spatial transcriptomics …