Fibroproliferative diseases, including the pulmonary fibroses, systemic sclerosis, liver
cirrhosis, cardiovascular disease, progressive kidney disease, and macular degeneration …

Fibrosis, or the accumulation of extracellular matrix molecules that make up scar tissue, is a
common feature of chronic tissue injury. Pulmonary fibrosis, renal fibrosis, and hepatic …

Fibrosis is the excessive deposition of extracellular matrix components, which results in
disruption of tissue architecture and loss of organ function. Fibrosis leads to high morbidity …

Human fibrotic diseases constitute a major health problem worldwide owing to the large
number of affected individuals, the incomplete knowledge of the fibrotic process …

Fibrosis contributes to the development of many diseases and many target molecules are
involved in fibrosis. Currently, the majority of fibrosis treatment strategies are limited to …

Fibrosis is a pathological scarring process that leads to destruction of organ architecture and
impairment of organ function. Chronic loss of organ function in most organs, including bone …

Myofibroblasts (MFs) play a critical role in the progression of chronic inflammatory and
fibroproliferative diseases in different tissues/organs, whatever the etiology. Fibrosis is …

Fibrosis, or tissue scarring, develops as a pathological deviation from the physiological
wound healing response and can occur in various organs such as the heart, lung, liver …

Fibrosis is characterized by the excessive extracellular matrix deposition due to
dysregulated wound and connective tissue repair response. Multiple organs can develop …

Fibrosis can affect any organ and is responsible for up to 45% of all deaths in the
industrialized world. It has long been thought to be relentlessly progressive and irreversible …