Effect of aspirin on long-term risk of colorectal cancer: consistent evidence from randomised and observational studies

E Flossmann, PM Rothwell - The Lancet, 2007 - thelancet.com
Background Randomised trials have shown that aspirin reduces the short-term risk of
recurrent colorectal adenomas in patients with a history of adenomas or cancer, but large …

Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials

PM Rothwell, M Wilson, CE Elwin, B Norrving, A Algra… - The Lancet, 2010 - thelancet.com
Background High-dose aspirin (≥ 500 mg daily) reduces long-term incidence of colorectal
cancer, but adverse effects might limit its potential for long-term prevention. The long-term …

Effects of regular aspirin on long-term cancer incidence and metastasis: a systematic comparison of evidence from observational studies versus randomised trials

AM Algra, PM Rothwell - The lancet oncology, 2012 - thelancet.com
Background Long-term follow-up of randomised trials of aspirin in prevention of vascular
events showed that daily aspirin reduced the incidence of colorectal cancer and several …

Prevention by daily soluble aspirin of colorectal adenoma recurrence: 4-year results of the APACC randomised trial

R Benamouzig, B Uzzan, J Deyra, A Martin, B Girard… - Gut, 2012 - gut.bmj.com
Background Aspirin inhibits colorectal carcinogenesis. In a randomised double-blind
placebo-controlled trial, daily soluble aspirin significantly reduced recurrence of colorectal …

Aspirin in the chemoprevention of colorectal neoplasia: an overview

AT Chan, N Arber, J Burn, WK Chia, P Elwood… - Cancer prevention …, 2012 - AACR
Considerable evidence supports the effectiveness of aspirin for chemoprevention of
colorectal cancer (CRC) in addition to its well-established benefits in the prevention of …

Daily soluble aspirin and prevention of colorectal adenoma recurrence: one-year results of the APACC trial

R Benamouzig, J Deyra, A Martin, B Girard, E Jullian… - Gastroenterology, 2003 - Elsevier
BACKGROUND & AIMS:: Epidemiologic and experimental studies have suggested that
aspirin intake reduces the risk for colorectal carcinogenesis. However, the available data are …

A population-based cohort study of the risk of colorectal and other cancers among users of low-dose aspirin

S Friis, HT Sørensen, JK McLaughlin… - British journal of …, 2003 - nature.com
Using data from the population-based Prescription Database of North Jutland County and
the Danish Cancer Registry, we compared cancer incidence among 29 470 individuals …

Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials

PM Rothwell, FGR Fowkes, JFF Belch, H Ogawa… - The Lancet, 2011 - thelancet.com
Background Treatment with daily aspirin for 5 years or longer reduces subsequent risk of
colorectal cancer. Several lines of evidence suggest that aspirin might also reduce risk of …

The use of aspirin for primary prevention of colorectal cancer: a systematic review prepared for the US Preventive Services Task Force

C Dubé, A Rostom, G Lewin, A Tsertsvadze… - Annals of internal …, 2007 - acpjournals.org
Background: Aspirin for prevention of colorectal cancer is controversial. Purpose: To
examine the benefits and harms of aspirin chemoprevention. Data Sources: MEDLINE, 1966 …

Reduced risk of colorectal cancer among long-term users of aspirin and nonaspirin nonsteroidal antiinflammatory drugs

LAG Rodríguez, C Huerta-Alvarez - Epidemiology, 2001 - journals.lww.com
Use of nonsteroidal antiinflammatory drugs (NSAIDs) has been associated with a reduced
risk of colorectal cancer, but limited information is available on the effect of individual …