Meta-analysis of gene expression studies in endometrial cancer identifies gene expression profiles associated with aggressive disease and patient outcome
Although endometrioid endometrial cancer (EEC; comprising~ 80% of all endometrial
cancers diagnosed) is typically associated with favourable patient outcome, a significant …
cancers diagnosed) is typically associated with favourable patient outcome, a significant …
Integration of genomic and clinical retrospective data to predict endometrioid endometrial cancer recurrence
J Gonzalez-Bosquet, S Gabrilovich… - International journal of …, 2022 - mdpi.com
Endometrial cancer (EC) incidence and mortality continues to rise. Molecular profiling of EC
promises improvement of risk assessment and treatment selection. However, we still lack …
promises improvement of risk assessment and treatment selection. However, we still lack …
Gene expression analysis of early stage endometrial cancers reveals unique transcripts associated with grade and histology but not depth of invasion
JI Risinger, J Allard, U Chandran, R Day… - Frontiers in …, 2013 - frontiersin.org
Endometrial cancer is the most common gynecologic malignancy in the United States but it
remains poorly understood at the molecular level. This investigation was conducted to …
remains poorly understood at the molecular level. This investigation was conducted to …
Endometrial cancer molecular characterization: the key to identifying high-risk patients and defining guidelines for clinical decision-making?
REM Baiden-Amissah, D Annibali, S Tuyaerts, F Amant - Cancers, 2021 - mdpi.com
Simple Summary Endometrial carcinomas (EC) have been traditionally classified based on
histopathology (types I and II). Determining the risk of a patient to experience disease …
histopathology (types I and II). Determining the risk of a patient to experience disease …
Development and validation of a RNAseq signature for prognostic stratification in endometrial cancer
G Beinse, MALF Belda, PA Just, N Bekmezian… - Gynecologic …, 2022 - Elsevier
Background Despite recent advances in endometrial carcinoma (EC) molecular
characterization, its prognostication remains challenging. We aimed to assess whether …
characterization, its prognostication remains challenging. We aimed to assess whether …
Molecular subtype stratified outcomes according to adjuvant therapy in endometrial cancer
A Jamieson, J Huvila, S Leung, D Chiu… - Gynecologic …, 2023 - Elsevier
Objectives Recent data support the predictive implications of molecular subtype assignment
in endometrial cancer (EC). Our objective was to retrospectively assess clinical outcomes …
in endometrial cancer (EC). Our objective was to retrospectively assess clinical outcomes …
Identification of potential crucial genes associated with the pathogenesis and prognosis of endometrial cancer
L Liu, J Lin, H He - Frontiers in genetics, 2019 - frontiersin.org
Background and Objective Endometrial cancer (EC) is a common gynecological malignancy
worldwide. Despite advances in the development of strategies for treating EC, prognosis of …
worldwide. Despite advances in the development of strategies for treating EC, prognosis of …
Histological grade of endometrioid endometrial cancer and relapse risk can be predicted with machine learning from gene expression data
P Gargya, BL Bálint - Cancers, 2021 - mdpi.com
Simple Summary Implementing machine learning methods into the RNA-seq data analysis
pipelines can further improve the efficiency of data utilization in clinical decision making. In …
pipelines can further improve the efficiency of data utilization in clinical decision making. In …
A 4-gene signature associated with recurrence in low-and intermediate-risk endometrial cancer
DAP de Andrade, LS da Silva, AC Laus… - Frontiers in …, 2021 - frontiersin.org
Background The molecular profile of endometrial cancer has become an important tool in
determining patient prognosis and their optimal adjuvant treatment. In addition to The …
determining patient prognosis and their optimal adjuvant treatment. In addition to The …
Microarray analysis reveals distinct gene expression profiles among different tumor histology, stage and disease outcomes in endometrial adenocarcinoma
P Mhawech-Fauceglia, D Wang, J Kesterson, K Clark… - PLoS …, 2010 - journals.plos.org
Background Endometrial cancer is the most common gynecologic malignancy in developed
countries and little is known about the underlying mechanism of stage and disease …
countries and little is known about the underlying mechanism of stage and disease …
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