Control of Candida albicans morphology and pathogenicity by post-transcriptional mechanisms

D Kadosh - Cellular and molecular life sciences, 2016 - Springer
Candida albicans is a major human fungal pathogen responsible for both systemic and
mucosal infections in a wide variety of immunocompromised individuals. Because the ability …

Regulatory mechanisms controlling morphology and pathogenesis in Candida albicans

D Kadosh - Current opinion in microbiology, 2019 - Elsevier
Highlights•There is a strong association between C. albicans morphology and virulence.•C.
albicans morphology control mechanisms may serve as important antifungal …

Post‐transcriptional gene regulation in the biology and virulence of Candida albicans

J Verma‐Gaur, A Traven - Cellular microbiology, 2016 - Wiley Online Library
In the human fungal pathogen Candida albicans, remodelling of gene expression drives
host adaptation and virulence. Recent studies revealed that in addition to transcription, post …

Overexpression approaches to advance understanding of Candida albicans

LS Rai, L van Wijlick, M Chauvel… - Molecular …, 2022 - Wiley Online Library
Candida albicans is an opportunistic fungal pathogen that is responsible for infections linked
to high mortality. Loss‐of‐function approaches, taking advantage of gene knockouts or …

Environmental Sensing and Signal Transduction Pathways Regulating Morphopathogenic Determinants of Candida albicans

S Biswas, P Van Dijck, A Datta - Microbiology and molecular …, 2007 - Am Soc Microbiol
Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, under certain environmental …

Transcriptional control of hyphal morphogenesis in Candida albicans

S Villa, M Hamideh, A Weinstock, MN Qasim… - FEMS yeast …, 2020 - academic.oup.com
Candida albicans is a multimorphic commensal organism and opportunistic fungal pathogen
in humans. A morphological switch between unicellular budding yeast and multicellular …

Morphogenesis in C. albicans

D Kadosh - Candida albicans: Cellular and molecular biology, 2017 - Springer
Many human fungal pathogens possess the ability to grow in a variety of different
morphologies and Candida albicans is no exception. In dimorphic fungal pathogens, such …

[HTML][HTML] Regulation of Candida albicans Hyphal Morphogenesis by Endogenous Signals

D Kornitzer - Journal of Fungi, 2019 - mdpi.com
Candida albicans is a human commensal fungus that is able to assume several
morphologies, including yeast, hyphal, and pseudohyphal. Under a range of conditions, C …

[HTML][HTML] A Versatile Overexpression Strategy in the Pathogenic Yeast Candida albicans: Identification of Regulators of Morphogenesis and Fitness

M Chauvel, A Nesseir, V Cabral, S Znaidi, S Goyard… - 2012 - journals.plos.org
Candida albicans is the most frequently encountered human fungal pathogen, causing both
superficial infections and life-threatening systemic diseases. Functional genomic studies …

Comparative evolution of morphological regulatory functions in Candida species

E Lackey, G Vipulanandan, DS Childers… - Eukaryotic cell, 2013 - Am Soc Microbiol
Morphological transitions play an important role in virulence and virulence-related
processes in a wide variety of pathogenic fungi, including the most commonly isolated …