DL‐3‐n‐butylphthalide promotes dendrite development in cortical neurons subjected to oxygen‐glucose deprivation/reperfusion
P Zhang, R Xu, Y Guo, J Qin, Y Dai… - Cell Biology …, 2018 - Wiley Online Library
The limited degree of functional recovery is closely associated with the condition of the
periinfarct cortex after ischemic stroke. The model of oxygen‐glucose deprivation in cultured …
periinfarct cortex after ischemic stroke. The model of oxygen‐glucose deprivation in cultured …
Delayed combinatorial treatment with flavopiridol and minocycline provides longer term protection for neuronal soma but not dendrites following global ischemia
GO Iyirhiaro, TB Brust, J Rashidian… - Journal of …, 2008 - Wiley Online Library
We previously reported that delayed administration of the general cyclin‐dependent kinase
inhibitor flavopiridol following global ischemia provided transient neuroprotection and …
inhibitor flavopiridol following global ischemia provided transient neuroprotection and …
NMDA receptor mediated dendritic plasticity in cortical cultures after oxygen-glucose deprivation
Z Lei, Y Ruan, AN Yang, ZC Xu - Neuroscience letters, 2006 - Elsevier
Dendrites and spines undergo dynamic changes in physiological and pathological
conditions. Dendritic outgrowth has been observed in surviving neurons months after …
conditions. Dendritic outgrowth has been observed in surviving neurons months after …
L-3-n-Butylphthalide reduces ischemic stroke injury and increases M2 microglial polarization
F Li, Q Ma, H Zhao, R Wang, Z Tao, Z Fan… - Metabolic brain …, 2018 - Springer
Overwhelming evidence suggests that microglia play an important role in ischemic injury
and they polarize into two different phenotypes with distinct functions after ischemic stroke …
and they polarize into two different phenotypes with distinct functions after ischemic stroke …
DL-3-n-butylphthalide protects endothelial cells against oxidative/nitrosative stress, mitochondrial damage and subsequent cell death after oxygen glucose …
L Li, B Zhang, Y Tao, Y Wang, H Wei, J Zhao, R Huang… - Brain research, 2009 - Elsevier
dl-3-n-butylphthalide (NBP) has been used for stroke treatment in China for years. Recently,
we found that NBP can reduce the incidence of stroke and have protective action on …
we found that NBP can reduce the incidence of stroke and have protective action on …
Dl-3-n-butylphthalide exerts neuroprotective effects by modulating hypoxia-inducible factor 1-alpha ubiquitination to attenuate oxidative stress-induced apoptosis
S Li, J Zhao, Y Xi, J Ren, Y Zhu, Y Lu… - Neural Regeneration …, 2023 - journals.lww.com
Abstract Dl-3-n-butylphthalide is used to treat mild and moderate acute ischemic stroke.
However, the precise underlying mechanism requires further investigation. In this study, we …
However, the precise underlying mechanism requires further investigation. In this study, we …
[HTML][HTML] Targeting phosphodiesterase 4 as a potential therapeutic strategy for enhancing neuroplasticity following ischemic stroke
Sensorimotor recovery following ischemic stroke is highly related with structural modification
and functional reorganization of residual brain tissues. Manipulations, such as treatment …
and functional reorganization of residual brain tissues. Manipulations, such as treatment …
The role of 7, 8-dihydroxyflavone in preventing dendrite degeneration in cortex after moderate traumatic brain injury
S Zhao, X Gao, W Dong, J Chen - Molecular neurobiology, 2016 - Springer
Our previous research showed that traumatic brain injury (TBI) induced by controlled cortical
impact (CCI) not only causes massive cell death, but also results in extensive dendrite …
impact (CCI) not only causes massive cell death, but also results in extensive dendrite …
Axonal outgrowth and dendritic plasticity in the cortical peri-infarct area after experimental stroke
Background and Purpose—Axonal remodeling is critical to brain repair after stroke. The
present study investigated axonal outgrowth after stroke and the signaling pathways …
present study investigated axonal outgrowth after stroke and the signaling pathways …
EphrinB2-EphB2 signaling for dendrite protection after neuronal ischemia in vivo and oxygen-glucose deprivation in vitro
Z Yu, W Li, J Lan, K Hayakawa, X Ji… - Journal of Cerebral …, 2021 - journals.sagepub.com
In order to rescue neuronal function, neuroprotection should be required not only for the
neuron soma but also the dendrites. Here, we propose the hypothesis that ephrin-B2-EphB2 …
neuron soma but also the dendrites. Here, we propose the hypothesis that ephrin-B2-EphB2 …