Pre-eclampsia is a condition unique to pregnancy and primarily affects the maternal and
placental vascular endothelium. It has significant morbidity and mortality consequences for …

Pre-eclampsia is a condition unique to pregnancy and primarily affects the maternal and
placental vascular endothelium. It has significant morbidity and mortality consequences for …

The causes of pre-eclampsia (PE) remain enigmatic, but there is a genetic component. The
diagnosis probably covers several conditions but it is, in any case, a multifactorial disease; …

Objective To investigate the potential perinatal effects of Factor V Leiden mutation and 5, 10
methylenetetrahydrofolate reductase C677T polymorphism in preeclamptic women. Study …

Pre-eclampsia is a progressive multisystem disorder that is exclusive to human pregnancy
and defined as new hypertension presenting after 20 weeks with significant proteinuria. It is …

Preeclampsia is a major cause of fetal and maternal morbidity. It has an incidence of 1–
5%(1). Manifested generally in the mid-to-late stages of gestation, preeclampsia is …

Preeclampsia is familial. Pedigree analyses suggest that one or more common alleles may
act as “preeclampsia susceptibility genes.” The authors speculate that genes involved in …

Background: Preeclampsia is a multisystem disorder involving vasoconstriction
andhypertension in the mother and decreased blood flow. There are inconsistent reportson …

Objective—To determine whether any simple, purely genetic mechanism can account for
susceptibility to pre‐eclampsia. Design—Six simple Mendelian models of inheritance were …

It is most unlikely that there is a single 'pre-eclampsia (PE) gene'. We are probably looking
for a cluster of polymorphisms which, possibly in conjunction with environmental factors …