Low levels of HDL cholesterol are a significant predictor of atherosclerotic cardiovascular
events. HDL is believed to protect against atherosclerosis by promoting reverse cholesterol …

This review aims to provide an overview on the properties of high‐density lipoproteins
(HDLs) and their cardioprotective effects. Emergent HDL therapies will be presented in the …

Hypercholesterolemia is one of the main risk factors for the development of atherosclerosis.
Among the various lipoprotein classes, however, high density lipoproteins (HDL) are …

The burden of atherothrombotic cardiovascular disease remains high despite currently
available optimum medical therapy. To address this substantial residual risk, the …

HDL-cholesterol and cardiovascular disease: rethinking our a... : Current Opinion in
Cardiology HDL-cholesterol and cardiovascular disease: rethinking our approach : Current …

Atherosclerosis is the underlying cause of heart attack and stroke. Early observations that
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …

Numerous epidemiological studies have identified high-density lipoprotein cholesterol
(HDL) to be an independent risk factor for coronary heart disease (CHD). HDL is an …

Low high-density lipoprotein cholesterol (HDL-C) characterizes an atherogenic dyslipidemia
that reflects adverse lifestyle choices, impaired metabolism, and increased cardiovascular …

Plasma concentrations of HDL cholesterol are inversely correlated with risk of coronary
heart disease, and low HDL-cholesterol levels are a risk factor even in patients aggressively …

Context: Statin treatment of cardiovascular patients reduces clinical events by 25 to 45%.
High-density lipoprotein (HDL) has been proposed as a therapeutic target to further reduce …