Improvement of the thalamocortical white matter network in people with stable treated relapsing–remitting multiple sclerosis over time

A Alshehri, N Koussis, O Al‐iedani, I Khormi… - NMR in …, 2024 - Wiley Online Library
Advanced imaging techniques (tractography) enable the mapping of white matter (WM)
pathways and the understanding of brain connectivity patterns. We combined tractography …

[HTML][HTML] A tractometry principal component analysis of white matter tract network structure and relationships with cognitive function in relapsing-remitting multiple …

D Jandric, GJM Parker, H Haroon, V Tomassini… - NeuroImage: Clinical, 2022 - Elsevier
Understanding the brain changes underlying cognitive dysfunction is a key priority in
multiple sclerosis (MS) to improve monitoring and treatment of this debilitating symptom …

[HTML][HTML] Injury to white matter tracts in relapsing–remitting multiple sclerosis: A possible therapeutic window within the first 5 years from onset using diffusion-tensor …

A Asaf, S Evan, A Anat - NeuroImage: Clinical, 2015 - Elsevier
DTI studies in multiple sclerosis (MS) reveal white matter (WM) injury that occurs with
disease progression. In the present study we aimed to elucidate the relationship of …

Increased structural white and grey matter network connectivity compensates for functional decline in early multiple sclerosis

V Fleischer, A Gröger, N Koirala… - Multiple Sclerosis …, 2017 - journals.sagepub.com
Background: The pathology of multiple sclerosis (MS) consists of demyelination and
neuronal injury, which occur early in the disease; yet, remission phases indicate repair …

Brain activity changes in cognitive networks in relapsing-remitting multiple sclerosis–insights from a longitudinal FMRI study

M Loitfelder, F Fazekas, K Koschutnig, S Fuchs… - PloS one, 2014 - journals.plos.org
Background Extrapolations from previous cross-sectional fMRI studies suggest cerebral
functional changes with progression of Multiple Sclerosis (MS), but longitudinal studies are …

Cross-sectional and longitudinal evaluation of white matter microstructure damage and cognitive correlations by automated fibre quantification in relapsing-remitting …

Z Yan, Z Tan, Q Zhu, Z Shi, J Feng, Y Wei, F Yin… - Brain Imaging and …, 2024 - Springer
The purpose of this study was to characterize whole-brain white matter (WM) fibre tracts by
automated fibre quantification (AFQ), capture subtle changes cross-sectionally and …

Gray matter integrity predicts white matter network reorganization in multiple sclerosis

A Radetz, N Koirala, J Krämer, A Johnen… - Human brain …, 2020 - Wiley Online Library
Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease leading to
gray matter atrophy and brain network reconfiguration as a response to increasing tissue …

Gray matter atrophy in relapsing-remitting multiple sclerosis is associated with white matter lesions in connecting fibers

M Bussas, S Grahl, V Pongratz… - Multiple Sclerosis …, 2022 - journals.sagepub.com
Background: Lesions of brain white matter (WM) and atrophy of brain gray matter (GM) are
well-established surrogate parameters in multiple sclerosis (MS), but it is unclear how …

Diffusion tensor imaging based network analysis detects alterations of neuroconnectivity in patients with clinically early relapsing‐remitting multiple sclerosis

Y Li, V Jewells, M Kim, Y Chen, A Moon… - Human brain …, 2013 - Wiley Online Library
Although it is inarguable that conventional MRI (cMRI) has greatly contributed to the
diagnosis and assessment of multiple sclerosis (MS), cMRI does not show close correlation …

Reduced White Matter Fiber Density in Patients with Multiple Sclerosis

Z Gharaylou, F Shahbodaghy, P Kolivand… - Brain …, 2024 - liebertpub.com
Introduction: Improved understanding of multiple sclerosis (MS) symptomatology, disease
mechanisms, and clinical effectiveness can be achieved by investigating microstructural …