Simple Summary Extracellular matrix is a three-dimensional network of macromolecules that
provide structural and biochemical support to surrounding cells. Extracellular matrix plays a …

The extracellular matrix (ECM) is present in all solid tissues and considered a master
regulator of cell behaviour and phenotype. The importance of maintaining the correct …

Extracellular matrix (ECM) is an essential component of the tumor microenvironment.
Cancer development and progression are associated with increased ECM deposition and …

Cancer is a term used for diseases that affect any organ in the body, in which abnormal cells
divide in an uncontrolled manner and in some instances are able to invade other tissues …

Solid tumors are complex organ-like structures that consist not only of tumor cells but also of
vasculature, extracellular matrix (ECM), stromal, and immune cells. Often, this tumor …

Extracellular matrix (ECM) is an essential component of the stromal microenvironment both
from a structural and a functional point of view. The ECM functions as a scaffold for tissue …

The extracellular matrix (ECM) surrounding cells is indispensable for regulating their
behavior. The dynamics of ECM signaling are tightly controlled throughout growth and …

The tumor microenvironment (TME) is composed of various cell types embedded in an
altered extracellular matrix (ECM). ECM not only serves as a support for tumor cell but also …

The main cause of cancer-related mortality, metastasis, is a complex, multi-step process.
The extracellular matrix (ECM) component of solid tumors has been implicated in metastatic …

The local microenvironment, or niche, of a cancer cell plays important roles in cancer
development. A major component of the niche is the extracellular matrix (ECM), a complex …