The essential role of the endothelium in vascular homeostasis is associated with the release
of endothelium-dependent relaxing and contractile factors (EDRF and EDCF, respectively) …

The last three decades witnessed the discovery of endothelium-derived relaxing factors
(EDRF)—such as prostacyclin, nitric oxide, and endothelium-derived hyperpolarizing factors …

The endothelium controls the tone of the underlying vascular smooth muscle mainly through
the production of vasodilator mediators. In some cases, this function is hampered by the …

The endothelium plays important roles in modulating vascular tone by synthesizing and
releasing a variety of endothelium-derived relaxing factors, including vasodilator …

Key discoveries in the past decade have revealed that the vascular endothelium is an
important regulatory organ that is involved in maintaining cardiovascular homeostasis in …

The endothelium can evoke relaxations (dilatations) of the underlying vascular smooth
muscle, by releasing vasodilator substances. The best characterized endothelium‐derived …

In most blood vessels, the endothelium generates both vasodilator and growth-stabilizing
mediators under normal physiological circumstances. The vasodilator influence of the …

The endothelium produces a variety of substances that play important roles in regulation of
the circulation and vascular wall homeostasis. The control of blood vessel wall homeostasis …

Since the detection of nitric oxide two and a half decades ago, there has been an incredible
boost in endothelial function research, which is fascinating the research community …

The vascular endothelium is much more than just a lining for blood vessels. It produces a
host of active substances and inactivates many mediators. The production of these …