Among the various bacterial infections, tuberculosis (TB) remains a life-threatening
infectious disease responsible as the most significant cause of mortality and morbidity …

Drugs inhibiting the iron scarcity-induced, siderophore-mediated iron-scavenging systems of
Mycobacterium tuberculosis (Mtb) and Yersinia pestis (Yp) may provide new therapeutic …

Tuberculosis is a major global health challenge and is far from being controlled.
Development of resistance to currently available drugs due to the successful adaptation of …

Tuberculosis nowadays ranks as the second leading cause of death from an infectious
disease worldwide. In the last twenty years, this disease has again started to spread mainly …

Tuberculosis remains a public health threat of global proportions. Iron is a scarce resource
indispensable to both host and pathogen during infection with Mycobacterium tuberculosis …

Tuberculosis (TB) caused by the pathogen Mycobacterium tuberculosis continues to be a
major worldwide health problem. Lack of compliance to the complex, multi-drug therapy …

Highlights•Mycobacterium tuberculosis causes more deaths than any other infectious
disease.•Heme-binding enzymes are crucial for M. tuberculosis survival in its human …

Iron is essential for the pathogenicity and virulence of Mycobacterium tuberculosis, which
synthesises salicyl‐capped siderophores (mycobactins) to acquire this element from the …

Tuberculosis (TB) is the world's biggest infectious disease killer. The increasing prevalence
of multidrug-resistant and extensively drug-resistant TB demonstrates that current treatments …

The highly contagious disease tuberculosis (TB) is caused by the bacterium Mycobacterium
tuberculosis (Mtb), which has been evolving drug resistance at an alarming rate. Like all …