[HTML][HTML] Circuit mechanisms of navigation strategy learning in mice

M Parrini, G Tricot, P Caroni, M Spolidoro - Current Biology, 2024 - cell.com
Navigation tasks involve the gradual selection and deployment of increasingly effective
searching procedures to reach targets. The brain mechanisms underlying such complex …

[HTML][HTML] Predictive maps in rats and humans for spatial navigation

W De Cothi, N Nyberg, EM Griesbauer, C Ghanamé… - Current Biology, 2022 - cell.com
Much of our understanding of navigation comes from the study of individual species, often
with specific tasks tailored to those species. Here, we provide a novel experimental and …

[HTML][HTML] Pathfinder: open source software for analyzing spatial navigation search strategies

MB Cooke, TP O'Leary, P Harris, R Ma, RE Brown… - …, 2019 - ncbi.nlm.nih.gov
Spatial navigation is a universal behavior that varies depending on goals, experience and
available sensory stimuli. Spatial navigational tasks are routinely used to study learning …

[HTML][HTML] Strategy dependent recruitment of distributed cortical circuits during spatial navigation

D Surinach, ML Rynes, K Saxena, E Ko… - Research …, 2023 - ncbi.nlm.nih.gov
Spatial navigation is a complex cognitive process that involves neural computations in
distributed regions of the brain. Little is known about how cortical regions are coordinated …

Goal-oriented searching mediated by ventral hippocampus early in trial-and-error learning

S Ruediger, D Spirig, F Donato, P Caroni - Nature neuroscience, 2012 - nature.com
Most behavioral learning in biology is trial and error, but how these learning processes are
influenced by individual brain systems is poorly understood. Here we show that ventral-to …

[HTML][HTML] Lesions of the dorsomedial striatum delay spatial learning and render cue-based navigation inflexible in a water maze task in mice

AS Lee, JM André, C Pittenger - Frontiers in behavioral neuroscience, 2014 - frontiersin.org
The dorsal striatum is involved in cue-based navigation strategies and in the development of
habits. It has been proposed that striatum-dependent cued navigation competes with …

[HTML][HTML] Retrosplenial cortical representations of space and future goal locations develop with learning

AMP Miller, W Mau, DM Smith - Current Biology, 2019 - cell.com
Recent findings suggest that long-term spatial and contextual memories depend on the
retrosplenial cortex (RSC)[1–5]. RSC damage impairs navigation in humans and rodents [6 …

[HTML][HTML] Complementary roles of the hippocampus and the dorsomedial striatum during spatial and sequence-based navigation behavior

C Fouquet, BM Babayan, A Watilliaux, B Bontempi… - PloS one, 2013 - journals.plos.org
We investigated the neural bases of navigation based on spatial or sequential egocentric
representation during the completion of the starmaze, a complex goal-directed navigation …

Conflict between place and response navigation strategies: effects on vicarious trial and error (VTE) behaviors

B Schmidt, A Papale, AD Redish… - Learning & …, 2013 - learnmem.cshlp.org
Navigation can be accomplished through multiple decision-making strategies, using
different information-processing computations. A well-studied dichotomy in these decision …

Search strategy selection in the Morris water maze indicates allocentric map formation during learning that underpins spatial memory formation

J Rogers, L Churilov, AJ Hannan, T Renoir - Neurobiology of learning and …, 2017 - Elsevier
Using a Matlab classification algorithm, we demonstrate that a highly salient distal cue array
is required for significantly increased likelihoods of spatial search strategy selection during …