Background and Purpose—Patients discovered to have a patent foramen ovale in the
setting of a cryptogenic stroke may be treated with percutaneous closure, antiplatelet …

Background Patent foramen ovale closure represents a potential secondary prevention
strategy for cryptogenic stroke, but available trials have varied by size, device studied, and …

Background The prevalence of patent foramen ovale among patients with cryptogenic stroke
is higher than that in the general population. Closure with a percutaneous device is often …

Background Whether closure of a patent foramen ovale is effective in the prevention of
recurrent ischemic stroke in patients who have had a cryptogenic stroke is unknown. We …

We pooled available data on follow-up events in patients with patent foramen ovale and
cryptogenic stroke to evaluate the net clinical benefit of different therapeutic strategies …

Background Whether closure of a patent foramen ovale reduces the risk of recurrence of
ischemic stroke in patients who have had a cryptogenic ischemic stroke is unknown …

Objectives: This study sought to perform a meta-analysis of randomized controlled trials
comparing device closure with medical therapy in the prevention of recurrent neurological …

The optimal therapy for prevention of recurrent stroke or transient ischemic attack in patients
with cryptogenic stroke and patent foramen ovale has not been defined. Although numerous …

Background We conducted a systematic review and meta‐analysis of randomized controlled
trials (RCT s) comparing patent foramen ovale (PFO) closure, anticoagulation, and …

Background: Among patients with a patent foramen ovale (PFO) and a prior cryptogenic
ischemic stroke or TIA, the absolute and relative risk of recurrent events is unclear. Methods …