Hydroxyapatite (HAp) as natural bone composition is highly osteoinductive. To harvest its
osteoinductivity in bone regenerative engineering, the HAp-supporting hydrogel is urgently …

Hydroxyapatite (HAp) as natural bone composition is highly osteoinductive. To harvest its
osteoinductivity in bone regenerative engineering, the HAp-supporting hydrogel is urgently …

Hydrogels are water-swollen networks with great potential for tissue engineering
applications. However, their use in bone regeneration is often hampered due to a lack of …

Current bone defect treatment strategies are associated with several risks and have major
limitations. Therefore, it is necessary to develop an inexpensive growth factor delivery …

A critical-sized bone defect, which cannot be repaired through self-healing, is a major
challenge in clinical therapeutics. The combination of biomimetic hydrogels and nano …

Formation of the native bone extracellular matrix (ECM) provides an attractive template for
bone tissue engineering. The structural support and biological complexity of bone ECM are …

Natural polysaccharide (NPH)-based injectable hydrogels have shown great potential for
critical-sized bone defect repair. However, their osteogenic, angiogenic, and mechanical …

Bioactive agents, including proteins and peptides, can be loaded into hydrogels to improve
bone regenerative capacity with their controlled release. However, the current loading …

Osteoporotic bone defects pose a significant challenge for bone regeneration as they exhibit
impaired healing capacity and delayed healing period. To address this issue, this study …

Hydrogels have been used as scaffolds for biomineralization in tissue engineering and
regenerative medicine for the repair and treatment of many tissue types. In the present work …