Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are
neuromuscular disorders that primarily affect boys due to an X-linked mutation in the DMD …

Duchenne muscular dystrophy (DMD) is a progressive, lethal, muscle wasting disease that
affects 1 of 3500 boys born worldwide. The disease results from mutation of the dystrophin …

Duchenne muscular dystrophy (DMD) is a neuromuscular disease characterized by
progressive weakness of the skeletal and cardiac muscles. This X-linked disorder is caused …

Duchenne and Becker muscular dystrophy (DMD and BMD) are related disorders that occur
because of mutations in the DMD gene, encoding the dystrophin protein. DMD is more …

Duchenne muscular dystrophy (DMD) is an X-linked, lethal muscle degenerative disease
caused by loss of dystrophin protein. DMD has no cure and few treatment options …

Clinical trials using strategies aimed at inducing dystrophin expression in Duchenne
muscular dystrophy (DMD) are underway or at advanced planning stage, including splice …

Aims Dystrophin, the protein product of the DMD gene, plays a critical role in muscle integrity
by stabilising the sarcolemma during contraction and relaxation. The DMD gene is …

Duchenne muscular dystrophy is a devastating inherited neuromuscular disorder that affects
one in 3300 live male births. Although the responsible gene and its product, dystrophin …

Dystrophin, the protein product of the gene related to Duchenne and Becker muscular
dystrophies, is a large cytoskeletal protein associated with the muscle fiber membrane …

The absence of the dystrophin protein in Duchenne muscular dystrophy (DMD) results in
myofiber fragility and a plethora of downstream secondary pathologies. Although a variety of …