Objective Recent studies have found aristaless-related homeobox gene (ARX)/pancreatic
and duodenal homeobox 1 (PDX1), alpha-thalassemia/mental retardation X-linked …

Abstract Purpose: Pancreatic neuroendocrine tumors (PanNET) are a heterogeneous group
of neoplasms with increasing incidence and unpredictable behavior. Whole-exome …

Purpose: Alternative lengthening of telomeres (ALT), a telomerase-independent telomere
maintenance mechanism, is strongly associated with ATRX and DAXX alterations and …

Background & Aims Sporadic pancreatic neuroendocrine tumors (pNETs) are rare and
genetically heterogeneous. Chromosome instability (CIN) has been detected in pNETs from …

Pancreatic neuroendocrine tumors (PanNETs) are rare neoplasms accounting for 1% to 2%
of all pancreatic tumors. The biological behavior of PanNETs is heterogeneous and …

Insulin-producing pancreatic neuroendocrine tumors (PanNETs)/insulinomas are generally
considered to be indolent tumors with an excellent prognosis after complete resection …

Background PanNETs shows heterogeneous biological behaviors. The aim was to
investigate prognostic markers based on most frequently mutated genes in PanNETs …

Objective: The aim of this study was to investigate the key molecular alterations in small
primary pancreatic neuroendocrine tumors (PanNETs) associated with the development of …

Despite prognostic grading and staging systems, it is a challenge to predict outcomes for
patients with pancreatic neuroendocrine tumors (PanNETs). Sequencing studies of …

Approximately 45% of sporadic well-differentiated pancreatic neuroendocrine tumors harbor
mutations in either ATRX (alpha thalassemia/mental retardation X-linked) or DAXX (death …