A microchambers containing contact lens for the noninvasive detection of tear exosomes

S Li, Y Zhu, R Haghniaz, S Kawakita… - Advanced Functional …, 2022 - Wiley Online Library
Exosomes, a form of small extracellular vesicles, play a crucial role in the metastasis of
cancers and thus are investigated as potential biomarkers for cancer diagnosis. However …

A pretreatment‐free, polymer‐based platform prepared by molecular imprinting and post‐imprinting modifications for sensing intact exosomes

K Mori, M Hirase, T Morishige, E Takano… - Angewandte …, 2019 - Wiley Online Library
Abstract Exosomes are small (30–100 nm) membrane vesicles that serve as regulatory
agents for intercellular communication in cancers. Currently, exosomes are detected by …

Discovering the Secret of Diseases by Incorporated Tear Exosomes Analysis via Rapid-Isolation System: iTEARS

L Hu, T Zhang, H Ma, Y Pan, S Wang, X Liu, X Dai… - ACS …, 2022 - ACS Publications
Nanoscale small extracellular vesicles (sEVs, exosomes) in tears allow us to investigate the
multisignatures of diseases. However, the translations of tear sEVs for biomarker discovery …

Antibody-conjugated signaling nanocavities fabricated by dynamic molding for detecting cancers using small extracellular vesicle markers from tears

T Takeuchi, K Mori, H Sunayama… - Journal of the …, 2020 - ACS Publications
Small extracellular vesicles (sEVs) are reliable biomarkers for early cancer detection;
however, conventional detection methods such as immune-based assays and microRNA …

Research progress of exosomes in pathogenesis, diagnosis, and treatment of ocular diseases

X Feng, Z Peng, L Yuan, M Jin, H Hu, X Peng… - … in Bioengineering and …, 2023 - frontiersin.org
Exosomes are natural extracellular vesicles with a diameter of 30–150 nm, which exist in
biological fluids and contain biomolecules related to the parent cell, such as proteins …

Covalently labeled fluorescent exosomes for in vitro and in vivo applications

MI González, M González-Arjona, A Santos-Coquillat… - Biomedicines, 2021 - mdpi.com
The vertiginous increase in the use of extracellular vesicles and especially exosomes for
therapeutic applications highlights the necessity of advanced techniques for gaining a …

Potential use of exosomes as diagnostic biomarkers and in targeted drug delivery: progress in clinical and preclinical applications

MN Huda, M Nafiujjaman, IG Deaguero… - ACS biomaterials …, 2021 - ACS Publications
Exosomes are cell-derived vesicles containing heterogeneous active biomolecules such as
proteins, lipids, mRNAs, receptors, immune regulatory molecules, and nucleic acids. They …

Emerging immunoassay technologies for the rapid detection of exosomes

C Liu, Y Qie, W Qin, K Zhao, J Zhu, L Zhao, M Li… - Sensors and Actuators B …, 2021 - Elsevier
Exosomes are a type of nano-scale biofilm-enclosed vesicles involved in intercellular
communications, which are actively secreted by almost all eukaryotes and have been …

Contact-lens biosensors

RC Tseng, CC Chen, SM Hsu, HS Chuang - Sensors, 2018 - mdpi.com
Rapid diagnosis and screening of diseases have become increasingly important in
predictive and preventive medicine as they improve patient treatment strategies and reduce …

Printed divisional optical biochip for multiplex visualizable exosome analysis at point‐of‐care

X Yang, Z Zhang, Y Wu, H Wang, Y Yun… - Advanced …, 2024 - Wiley Online Library
Rapid detection of various exosomes is of great significance in early diagnosis and
postoperative monitoring of cancers. Here, a divisional optical biochip is reported for …