Pertussis is a highly communicable acute respiratory infection caused by Bordetella
pertussis. Immunity is not lifelong after natural infection or vaccination. Pertussis outbreaks …

Current acellular pertussis vaccines have various shortcomings, which may contribute to
their suboptimal efficacy and waning immunity in vaccinated populations. This calls for the …

Pertussis is a common respiratory infection caused by the bacterium Bordetella pertussis.
Although most cases occur in developing countries, it is considered endemic globally. The …

Pertussis is an acute respiratory disease caused by Bordetella pertussis. Due to its
frequency and severity, prevention of pertussis has been considered an important public …

Vaccines against pertussis have been used for more than a hundred years. This review
describes the development of whole-cell (wP) and acellular pertussis (aP) vaccines, which …

Introduction Whole cell and acellular pertussis vaccines have been very effective in
decreasing the deaths of neonates and infants from Bordetella pertussis. Despite high …

Recent data indicate that Bordetella pertussis can be an important cause of illness in
adolescents and adults. In a randomized observer-and subject-blinded study, adults (≥ 18 …

Pertussis or whooping cough, caused by Bordetella pertussis, is a severe respiratory
disease that can be fatal in young infants. Two types of vaccines are available and widely …

Routine use of pertussis vaccines has diminished the incidence of this disease but has not
eliminated the pathogen. Pertussis remains a significant cause of disease in both very …

Pertussis (whooping cough) is a respiratory disease caused by the bacterium Bordetella
pertussis. Despite the implementation of immunization programs and high vaccine coverage …